Publications

Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature.

Le Gras S(1), Keime C(1), Anthony A(2,)(3), Lotz C(2,)(3), De Longprez L(4,)(5), Brouillet E(4,)(5), Cassel JC(2,)(3), Boutillier AL(2,)(3), Merienne K(2,)(3).

Sci Rep 2017; 7():42875

Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression.

Duc C(1), Benoit M(2), Detourne G(3), Simon L(4), Poulet A(5), Jung M(6), Veluchamy A(7), Latrasse D(8), Le Goff S(5), Cotterell S(5), Tatout C(5), Benhamed M(9), Probst AV(10).

Plant Cell 2017; (0):0

B cells differentiate in Human thymus and express AIRE.

Gies V(1), Guffroy A(1), Danion F(1), Billaud P(2), Keime C(3), Fauny JD(4), Susini S(5), Soley A(4), Martin T(6), Pasquali JL(6), Gros F(7), Andre-Schmutz I(5), Soulas-Sprauel P(8), Korganow AS(9).

J Allergy Clin Immunol 2017; 139(3):1049-1052

Blepharocheilodontic syndrome is a CDH1 pathway-related disorder due to mutations in CDH1 and CTNND1.

Ghoumid J(1,)(2,)(3), Stichelbout M(1,)(2), Jourdain AS(2,)(4), Frenois F(1,)(2), Lejeune-Dumoulin S(1), Alex-Cordier MP(5), Lebrun M(6), Guerreschi P(2,)(3,)(7), Duquennoy-Martinot V(2,)(3,)(7), Vinchon M(2,)(3,)(8), Ferri J(3,)(9), Jung M(10), Vicaire S(10), Vanlerberghe C(1,)(2,)(3), Escande F(2,)(4), Petit F(1,)(2,)(3), Manouvrier-Hanu S(1,)(2,)(3).

Genet Med 2017; (0):0

Combinatorial DNA methylation codes at repetitive elements.

Papin C(1), Ibrahim A(1), Le Gras S(1), Velt A(1), Jost B(1), Stoll I(1), Menoni H(2), Bronner C(1), Dimitrov S(2), Hamiche A(3).

Genome Res 2017; (0):0

Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups.

Krieger V(1), Hamacher A(1), Gertzen CGW(1), Senger J(2), Zwinderman MRH(3), Marek M(4), Romier C(4), Dekker FJ(3), Kurz T(1), Jung M(2), Gohlke H(1), Kassack MU(1), Hansen FK(1)(5).

J Med Chem 2017; (0):0

Genome-wide Analysis of RARbeta Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.

Niewiadomska-Cimicka A(1)(2)(3)(4)(5), Krzyzosiak A(1)(2)(3)(4)(5)(6), Ye T(1)(2)(3)(4), Podlesny-Drabiniok A(1)(2)(3)(4)(5), Dembele D(1)(2)(3)(4), Dolle P(1)(2)(3)(4)(5), Krezel W(7)(8)(9)(10)(11).

Mol Neurobiol 2017; 54(5):3859-3878

Inhibition of beta-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis.

Henriques A(1)(2)(3), Huebecker M(4), Blasco H(5)(6), Keime C(7), Andres CR(5)(6), Corcia P(5)(8), Priestman DA(4), Platt FM(4), Spedding M(3), Loeffler JP(9)(10).

Sci Rep 2017; 7(1):5235

Intragenic FMR1 disease-causing variants: a significant mutational mechanism leading to Fragile-X syndrome.

Quartier A(1,)(2,)(3,)(4), Poquet H(5,)(6), Gilbert-Dussardier B(7), Rossi M(8), Casteleyn AS(9), Portes VD(10), Feger C(11), Nourisson E(11), Kuentz P(5,)(6), Redin C(1,)(2,)(3,)(4), Thevenon J(5,)(6), Mosca-Boidron AL(12), Callier P(12), Muller J(11,)(13), Lesca G(8), Huet F(6), Geoffroy V(13), El Chehadeh S(6,)(14), Jung M(1,)(2,)(3,)(4), Trojak B(15), Le Gras S(1,)(2,)(3,)(4), Lehalle D(5), Jost B(1,)(2,)(3,)(4), Maury S(14), Masurel A(6), Edery P(8), Thauvin-Robinet C(5,)(6), Gerard B(11), Mandel JL(1,)(2,)(3,)(4,)(11,)(16,)(17), Faivre L(5,)(6), Piton A(1,)(11).

Eur J Hum Genet 2017; 25(4):423-431

Isophthalic Acid-Based HDAC Inhibitors as Potent Inhibitors of HDAC8 from Schistosoma mansoni.

Stenzel K(1), Chakrabarti A(2), Melesina J(3), Hansen FK(1)(4), Lancelot J(5), Herkenhohner S(1), Lungerich B(1), Marek M(6), Romier C(6), Pierce RJ(5), Sippl W(3), Jung M(2), Kurz T(1).

Arch Pharm (Weinheim) 2017; (0):0

Macrophage production and activation are dependent on TRIM33.

Gallouet AS(1,)(2,)(3,)(4,)(5), Ferri F(1,)(2,)(3,)(4,)(5,)(6), Petit V(1,)(2,)(3,)(4,)(5), Parcelier A(1,)(2,)(3,)(4,)(5), Lewandowski D(1,)(2,)(3,)(4,)(5), Gault N(1,)(2,)(3,)(4,)(5), Barroca V(1,)(2,)(3,)(4,)(5), Le Gras S(6), Soler E(1,)(2,)(3,)(4,)(7), Grosveld F(7), Davidson I(6), Romeo PH(1,)(2,)(3,)(4,)(5).

Oncotarget 2017; 8(3):5111-5122

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.

Joshi S(1), Davidson G(1), Le Gras S(1), Watanabe S(2), Braun T(2), Mengus G(1), Davidson I(1).

PLoS Genet 2017; 13(2):e1006600

Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression.

Tarabay Y(1,)(2,)(3), Achour M(1,)(3), Teletin M(1,)(4), Ye T(1), Teissandier A(5), Mark M(1,)(4), Bourc'his D(5), Viville S(6,)(7).

J Cell Sci 2017; (0):0

The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility.

Jegu T(1)(2)(3), Veluchamy A(4), Ramirez-Prado JS(1)(4), Rizzi-Paillet C(1), Perez M(1), Lhomme A(1), Latrasse D(1), Coleno E(1), Vicaire S(5), Legras S(5), Jost B(5), Rougee M(6), Barneche F(6), Bergounioux C(1), Crespi M(1), Mahfouz MM(4), Hirt H(1)(4), Raynaud C(1), Benhamed M(7)(8).

Genome Biol 2017; 18(1):114

A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement.

Prasad MK(1), Geoffroy V(1), Vicaire S(2), Jost B(2), Dumas M(2), Le Gras S(2), Switala M(3), Gasse B(4), Laugel-Haushalter V(5), Paschaki M(6), Leheup B(7), Droz D(8), Dalstein A(8), Loing A(9), Grollemund B(10), Muller-Bolla M(11), Lopez-Cazaux S(12), Minoux M(3), Jung S(3), Obry F(3), Vogt V(3), Davideau JL(10), Davit-Beal T(13), Kaiser AS(14), Moog U(14), Richard B(15), Morrier JJ(15), Duprez JP(15), Odent S(16), Bailleul-Forestier I(17), Rousset MM(18), Merametdijan L(19), Toutain A(20), Joseph C(21), Giuliano F(22), Dahlet JC(9), Courval A(23), El Alloussi M(24), Laouina S(24), Soskin S(25), Guffon N(26), Dieux A(27), Doray B(28), Feierabend S(29), Ginglinger E(30), Fournier B(31), de la Dure Molla M(31), Alembik Y(28), Tardieu C(32), Clauss F(3), Berdal A(31), Stoetzel C(1), Manière MC(3), Dollfus H(33), Bloch-Zupan A(34).

J Med Genet 2016; 53(2):98-110

Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes.

Dembele D(1,)(2), Kastner P(3,)(4).

BMC Bioinformatics 2016; 17(1):462

Enterocyte Purge and Rapid Recovery Is a Resilience Reaction of the Gut Epithelium to Pore-Forming Toxin Attack.

Lee KZ(1), Lestradet M(2), Socha C(2), Schirmeier S(2), Schmitz A(3), Spenle C(4), Lefebvre O(4), Keime C(5), Yamba WM(2), Bou Aoun R(2), Liegeois S(2), Schwab Y(5), Simon-Assmann P(4), Dalle F(6), Ferrandon D(7).

Cell Host Microbe 2016; 20(6):716-730

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.

Langer D(1), Martianov I(1), Alpern D(1,)(2), Rhinn M(3), Keime C(1), Dolle P(3), Mengus G(1), Davidson I(1).

Nat Commun 2016; 7():11063

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids.

Weger BD(1,)(2), Weger M(1,)(3), Gorling B(4,)(5), Schink A(1), Gobet C(2,)(6), Keime C(7), Poschet G(8), Jost B(7), Krone N(9), Hell R(8), Gachon F(2,)(6), Luy B(4,)(5), Dickmeis T(1).

PLoS Genet 2016; 12(12):e1006512

Fast Dating Using Least-Squares Criteria and Algorithms.

To TH(1), Jung M(2), Lycett S(3), Gascuel O(4).

Syst Biol 2016; 65(1):82-97

Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons.

Tabet R(1), Moutin E(2), Becker JA(1), Heintz D(3), Fouillen L(4), Flatter E(1), Krezel W(1), Alunni V(1), Koebel P(1), Dembélé D(1), Tassone F(5), Bardoni B(6), Mandel JL(7), Vitale N(8), Muller D(2), Le Merrer J(1), Moine H(9).

Proc Natl Acad Sci U S A 2016; 113(26):E3619-28

Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells.

de Dieuleveult M(1), Yen K(2,)(3), Hmitou I(1), Depaux A(1), Boussouar F(1,)(4), Dargham DB(1), Jounier S(1), Humbertclaude H(1), Ribierre F(5), Baulard C(5), Farrell NP(3), Park B(3), Keime C(6), Carrière L(1), Berlivet S(1), Gut M(7), Gut I(7), Werner M(1), Deleuze JF(5), Olaso R(5), Aude JC(1), Chantalat S(5), Pugh BF(3), Gérard M(1).

Nature 2016; 530(7588):113-6

Hemidesmosome integrity protects the colon against colitis and colorectal cancer.

De Arcangelis A(1), Hamade H(2), Alpy F(3), Normand S(4), Bruyère E(5), Lefebvre O(6), Méchine-Neuville A(7), Siebert S(1), Pfister V(1), Lepage P(8), Laquerriere P(9), Dembele D(1), Delanoye-Crespin A(4), Rodius S(10), Robine S(11), Kedinger M(12), Van Seuningen I(5), Simon-Assmann P(6), Chamaillard M(4), Labouesse M(13), Georges-Labouesse E(1).

Gut 2016; (0):0

Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis.

Bandiera S(1), Pernot S(1), El Saghire H(1), Durand SC(1), Thumann C(1), Crouchet E(1), Ye T(2), Fofana I(3), Oudot MA(1), Barths J(1), Schuster C(1), Pessaux P(4), Heim MH(3), Baumert TF(5), Zeisel MB(6).

J Virol 2016; 90(14):6387-400

Reduced DICER1 Expression Bestows Rheumatoid Arthritis Synoviocytes Proinflammatory Properties and Resistance to Apoptotic Stimuli.

Alsaleh G(1), Nehmar R(1), Blüml S(2), Schleiss C(1), Ostermann E(3), Dillenseger JP(4), Sayeh A(5), Choquet P(4), Dembele D(6), Francois A(3), Salmon JH(7), Paul N(1), Schabbauer G(8), Bierry G(9), Meyer A(10), Gottenberg JE(3), Haas G(11), Pfeffer S(11), Vallat L(1), Sibilia J(12), Bahram S(1), Georgel P(1).

Arthritis Rheumatol 2016; 68(8):1839-48

Reversal of Pathologic Lipid Accumulation in NPC1-Deficient Neurons by Drug-Promoted Release of LAMP1-Coated Lamellar Inclusions.

Demais V(1), Barthélémy A(2), Perraut M(2), Ungerer N(2), Keime C(3), Reibel S(4), Pfrieger FW(5).

J Neurosci 2016; 36(30):8012-25

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

Freyermuth F(1), Rau F(2), Kokunai Y(3), Linke T(4), Sellier C(1), Nakamori M(3), Kino Y(5), Arandel L(2), Jollet A(2), Thibault C(1), Philipps M(1), Vicaire S(1), Jost B(1), Udd B(6,)(7,)(8), Day JW(9), Duboc D(10), Wahbi K(10), Matsumura T(11), Fujimura H(11), Mochizuki H(3), Deryckere F(12), Kimura T(13), Nukina N(14), Ishiura S(15), Lacroix V(16), Campan-Fournier A(17), Navratil V(18), Chautard E(19), Auboeuf D(19), Horie M(20), Imoto K(21), Lee KY(22), Swanson MS(23), Lopez de Munain A(24), Inada S(25), Itoh H(20), Nakazawa K(25), Ashihara T(20), Wang E(23), Zimmer T(4), Furling D(2), Takahashi MP(3), Charlet-Berguerand N(1).

Nat Commun 2016; 7():11067

Vine nitrogen status and volatile thiols and their precursors from plot to transcriptome level.

Helwi P(1,)(2,)(3), Guillaumie S(1,)(3), Thibon C(4,)(5), Keime C(6), Habran A(1,)(3), Hilbert G(1,)(3), Gomes E(1,)(3), Darriet P(4,)(5), Delrot S(1,)(3), van Leeuwen C(7).

BMC Plant Biol 2016; 16(1):173

A Brn2-Zic1 axis specifies the neuronal fate of retinoic-acid-treated embryonic stem cells.

Urban S(1), Kobi D(1), Ennen M(1), Langer D(1), Le Gras S(1), Ye T(1), Davidson I(2).

J Cell Sci 2015; 128(13):2303-18

Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

Koludrovic D(1), Laurette P(2), Strub T(3), Keime C(2), Le Coz M(4), Coassolo S(2), Mengus G(2), Larue L(5), Davidson I(6).

PLoS Genet 2015; 11(10):e1005555

Circulating Human Eosinophils Share a Similar Transcriptional Profile in Asthma and Other Hypereosinophilic Disorders.

Barnig C(1), Alsaleh G(2), Jung N(3), Dembélé D(4), Paul N(2), Poirot A(5), Uring-Lambert B(6), Georgel P(2), de Blay F(5), Bahram S(7).

PLoS One 2015; 10(11):e0141740

Constitutive arsenite oxidase expression detected in arsenic-hypertolerant Pseudomonas xanthomarina S11.

Koechler S(1), Arsène-Ploetze F(2), Brochier-Armanet C(3), Goulhen-Chollet F(4), Heinrich-Salmeron A(5), Jost B(6), Lièvremont D(7), Philipps M(8), Plewniak F(9), Bertin PN(10), Lett MC(11).

Res Microbiol 2015; 166(3):205-14

Deletion of the App-Runx1 region in mice models human partial monosomy 21.

Arbogast T(1), Raveau M(1), Chevalier C(1), Nalesso V(1), Dembele D(1), Jacobs H(2), Wendling O(2), Roux M(3), Duchon A(1), Herault Y(4).

Dis Model Mech 2015; 8(6):623-34

Early adaptive response of the retina to a pro-diabetogenic diet: Impairment of cone response and gene expression changes in high-fructose fed rats.

Thierry M(1), Pasquis B(1), Buteau B(1), Fourgeux C(1), Dembele D(2), Leclere L(1), Gambert-Nicot S(3), Acar N(1), Bron AM(4), Creuzot-Garcher CP(4), Bretillon L(5).

Exp Eye Res 2015; 135():37-46

Endogenous siRNAs and piRNAs derived from transposable elements and genes in the malaria vector mosquito Anopheles gambiae.

Biryukova I(1), Ye T(2).

BMC Genomics 2015; 16(1):278

Genome-Wide Mapping of Collier In Vivo Binding Sites Highlights Its Hierarchical Position in Different Transcription Regulatory Networks.

de Taffin M(1), Carrier Y(1), Dubois L(1), Bataillé L(1), Painset A(2), Le Gras S(3), Jost B(3), Crozatier M(1), Vincent A(1).

PLoS One 2015; 10(7):e0133387

Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2.

Oravecz A(1), Apostolov A(1), Polak K(1), Jost B(2), Le Gras S(2), Chan S(1), Kastner P(1,)(3).

Nat Commun 2015; 6():8823

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.

Achour M(1), Le Gras S(2), Keime C(2), Parmentier F(3), Lejeune FX(3), Boutillier AL(4), Néri C(3), Davidson I(5), Merienne K(6).

Hum Mol Genet 2015; 24(12):3481-96

No evidence for generation of alternatively spliced isoforms from the mutated Trim24 allele lacking exon 4 in mouse liver.

Herquel B(1), Keime C(2), Davidson I(3).

J Hepatol 2015; 63(1):276-7

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

Brault V(1), Duchon A(1), Romestaing C(2), Sahun I(3), Pothion S(4), Karout M(1), Borel C(5), Dembele D(1), Bizot JC(6), Messaddeq N(1), Sharp AJ(7), Roussel D(2), Antonarakis SE(8), Dierssen M(3), Herault Y(9).

PLoS Genet 2015; 11(3):e1005062

Single-cell gene expression signatures reveal melanoma cell heterogeneity.

Ennen M(1), Keime C(1), Kobi D(1), Mengus G(1), Lipsker D(2), Thibault-Carpentier C(1), Davidson I(1).

Oncogene 2015; 34(25):3251-63

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.

Laurette P(1), Strub T(1), Koludrovic D(1), Keime C(1), Le Gras S(1), Seberg H(2), Van Otterloo E(2), Imrichova H(3), Siddaway R(4), Aerts S(3), Cornell RA(2), Mengus G(1), Davidson I(1).

Elife 2015; 4():e06857

Ultradeep sequencing in the therapeutic management of HIV-1 infection at treatment initiation.

Todesco E(1), Mercier-Darty M(2), Jung M(3), Bottero J(4), Boyd A(5), Marcelin AG(6), Calvez V(6), Morand-Joubert L(7).

J Antimicrob Chemother 2015; 70(6):1919-20

20 ans apres: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition.

Piton A(1), Poquet H(2), Redin C(1), Masurel A(3), Lauer J(4), Muller J(5), Thevenon J(6), Herenger Y(4), Chancenotte S(7), Bonnet M(8), Pinoit JM(9), Huet F(3), Thauvin-Robinet C(6), Jaeger AS(4), Le Gras S(10), Jost B(10), Gérard B(4), Peoc'h K(11), Launay JM(11), Faivre L(6), Mandel JL(12).

Eur J Hum Genet 2014; 22(6):776-83

Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing.

Redin C(1), Gérard B(2), Lauer J(2), Herenger Y(2), Muller J(3), Quartier A(1), Masurel-Paulet A(4), Willems M(5), Lesca G(6), El-Chehadeh S(4), Le Gras S(7), Vicaire S(7), Philipps M(7), Dumas M(7), Geoffroy V(8), Feger C(7), Haumesser N(1), Alembik Y(9), Barth M(10), Bonneau D(10), Colin E(10), Dollfus H(11), Doray B(9), Delrue MA(12), Drouin-Garraud V(13), Flori E(9), Fradin M(14), Francannet C(15), Goldenberg A(13), Lumbroso S(16), Mathieu-Dramard M(17), Martin-Coignard D(18), Lacombe D(12), Morin G(17), Polge A(16), Sukno S(19), Thauvin-Robinet C(4), Thevenon J(4), Doco-Fenzy M(20), Genevieve D(5), Sarda P(5), Edery P(6), Isidor B(21), Jost B(7), Olivier-Faivre L(4), Mandel JL(22), Piton A(1).

J Med Genet 2014; 51(11):724-36

Fold change rank ordering statistics: a new method for detecting differentially expressed genes.

Dembélé D(1), Kastner P.

BMC Bioinformatics 2014; 15():14

Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts.

Al Tanoury Z(1), Piskunov A, Andriamoratsiresy D, Gaouar S, Lutzing R, Ye T, Jost B, Keime C, Rochette-Egly C.

J Cell Sci 2014; 127(Pt 3):521-33

Interpreting and visualizing ChIP-seq data with the seqMINER software.

Ye T(1), Ravens S, Krebs AR, Tora L.

Methods Mol Biol 2014; 1150(Chap 8):141-52

Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation.

Ravens S(1), Fournier M(1), Ye T(2), Stierle M(1), Dembele D(2), Chavant V(3), Tora L(1).

Elife 2014; 3():e02104

Phosphorylation of the retinoic acid receptor RARgamma2 is crucial for the neuronal differentiation of mouse embryonic stem cells.

Al Tanoury Z(1), Gaouar S, Piskunov A, Ye T, Urban S, Jost B, Keime C, Davidson I, Dierich A, Rochette-Egly C.

J Cell Sci 2014; 127(PT 9):2095-2105

Rfx6 maintains the functional identity of adult pancreatic beta cells.

Piccand J(1), Strasser P(1), Hodson DJ(2), Meunier A(1), Ye T(1), Keime C(1), Birling MC(3), Rutter GA(2), Gradwohl G(4).

Cell Rep 2014; 9(6):2219-32

T-cell factor 4 and beta-catenin chromatin occupancies pattern zonal liver metabolism in mice.

Gougelet A(1), Torre C, Veber P, Sartor C, Bachelot L, Denechaud PD, Godard C, Moldes M, Burnol AF, Dubuquoy C, Terris B, Guillonneau F, Ye T, Schwarz M, Braeuning A, Perret C, Colnot S.

Hepatology 2014; 59(6):2344-57

TAF4 Inactivation Reveals the 3 Dimensional Growth Promoting Activities of Collagen 6A3.

Martianov I(1), Cler E(1), Duluc I(2), Vicaire S(1), Philipps M(1), Freund JN(2), Davidson I(1).

PLoS One 2014; 9(2):e87365

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

Alpern D(1), Langer D(1), Ballester B(2), Le Gras S(1), Romier C(3), Mengus G(1), Davidson I(1).

Elife 2014; 3():e03613

The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response.

Robertson ED(1), Wasylyk C(1), Ye T(1), Jung AC(2), Wasylyk B(1).

PLoS One 2014; 9(11):e113050

The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.

Geimer Le Lay AS(1), Oravecz A, Mastio J, Jung C, Marchal P, Ebel C, Dembélé D, Jost B, Le Gras S, Thibault C, Borggrefe T, Kastner P, Chan S.

Sci Signal 2014; 7(317):ra28

Transcriptome-wide analysis of microRNA expression in the malaria mosquito Anopheles gambiae.

Biryukova I(1), Ye T, Levashina E.

BMC Genomics 2014; 15():557

UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells.

Gyenis A(1), Umlauf D(1), Ujfaludi Z(2), Boros I(2), Ye T(3), Tora L(1).

PLoS Genet 2014; 10(7):e1004483

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis.

Dillies MA, Rau A, Aubert J, Hennequet-Antier C, Jeanmougin M, Servant N, Keime C, Marot G, Castel D, Estelle J, Guernec G, Jagla B, Jouneau L, Laloë D, Le Gall C, Schaëffer B, Le Crom S, Guedj M, Jaffrézic F; on behalf of The French StatOmique Consortium.

Brief Bioinform 2013; 14(6):671-683

An integrated diagnosis strategy for congenital myopathies.

Böhm J, Vasli N, Malfatti E, Le Gras S, Feger C, Jost B, Monnier N, Brocard J, Karasoy H, Gérard M, Walter MC, Reilich P, Biancalana V, Kretz C, Messaddeq N, Marty I, Lunardi J, Romero NB, Laporte J.

PLoS One 2013; 8(6):e67527

beta-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL.

Kaveri D, Kastner P, Dembélé D, Nerlov C, Chan S, Kirstetter P.

Blood 2013; 122(5):694-704

Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA.

Fadloun A(1), Le Gras S, Jost B, Ziegler-Birling C, Takahashi H, Gorab E, Carninci P, Torres-Padilla ME.

Nat Struct Mol Biol 2013; 20(3):332-8

Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome.

Koutsopoulos OS, Kretz C, Weller CM, Roux A, Mojzisova H, Böhm J, Koch C, Toussaint A, Heckel E, Stemkens D, Ter Horst SA, Thibault C, Koch M, Mehdi SQ, Bijlsma EK, Mandel JL, Vermot J, Laporte J.

Eur J Hum Genet 2013; 21(6):637-42

Genetic analysis of the biosynthesis of 2-methoxy-3-isobutylpyrazine, a major grape-derived aroma compound impacting wine quality.

Guillaumie S, Ilg A, Réty S, Brette M, Trossat-Magnin C, Decroocq S, Léon C, Keime C, Ye T, Baltenweck-Guyot R, Claudel P, Bordenave L, Vanbrabant S, Duchêne E, Delrot S, Darriet P, Hugueney P, Gomès E.

Plant Physiol 2013; 162(2):604-15

Genome Sequence of Halomonas sp. Strain A3H3, Isolated from Arsenic-Rich Marine Sediments.

Koechler S(1), Plewniak F, Barbe V, Battaglia-Brunet F, Jost B, Joulian C, Philipps M, Vicaire S, Vincent S, Ye T, Bertin PN.

Genome Announc 2013; 1(5):e00819-13

Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs.

Mukherji A(1), Kobiita A, Ye T, Chambon P.

Cell 2013; 153(4):812-27

Molars and incisors: show your microarray IDs.

Laugel-Haushalter V, Paschaki M, Thibault-Carpentier C, Dembelé D, Dollé P, Bloch-Zupan A.

BMC Res Notes 2013; 6():113

Sequestration of DROSHA and DGCR8 by Expanded CGG RNA Repeats Alters MicroRNA Processing in Fragile X-Associated Tremor/Ataxia Syndrome.

Sellier C, Freyermuth F, Tabet R, Tran T, He F, Ruffenach F, Alunni V, Moine H, Thibault C, Page A, Tassone F, Willemsen R, Disney MD, Hagerman PJ, Todd PK, Charlet-Berguerand N.

Cell Rep 2013; 3(3):869-80

Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.

Neyret-Kahn H(1), Benhamed M, Ye T, Le Gras S, Cossec JC, Lapaquette P, Bischof O, Ouspenskaia M, Dasso M, Seeler J, Davidson I, Dejean A.

Genome Res 2013; 23(10):1563-79

TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs.

Ballarino M, Jobert L, Dembélé D, de la Grange P, Auboeuf D, Tora L.

Oncogene 2013; 32(39):4646-55

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature

Fouillade C., Baron-Menguy C., Domenga-Denier V., Thibault C., Takamiya K., Huganir R., Joutel A.

Arteriosclerosis, thrombosis, and vascular biology 2013; 33(1):76-86

Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling.

Paschaki M, Schneider C, Rhinn M, Thibault-Carpentier C, Dembélé D, Niederreither K, Dollé P.

PLoS One 2013; 8(4):e62274

Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA.

Herquel B, Ouararhni K, Martianov I, Le Gras S, Ye T, Keime C, Lerouge T, Jost B, Cammas F, Losson R, Davidson I.

Nat Struct Mol Biol 2013; 20(3):339-46

Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice.

Ritié L(1), Spenlé C, Lacroute J, Bolcato-Bellemin AL, Lefebvre O, Bole-Feysot C, Jost B, Klein A, Arnold C, Kedinger M, Bagnard D, Orend G, Simon-Assmann P.

PLoS One 2012; 7(5):e37710

Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells.

Carrière L, Graziani S, Alibert O, Ghavi-Helm Y, Boussouar F, Humbertclaude H, Jounier S, Aude JC, Keime C, Murvai J, Foglio M, Gut M, Gut I, Lathrop M, Soutourina J, Gérard M, Werner M.

Nucleic Acids Res 2012; 40(1):270-83

Next generation sequencing for molecular diagnosis of neuromuscular diseases.

Vasli N, Böhm J, Le Gras S, Muller J, Pizot C, Jost B, Echaniz-Laguna A, Laugel V, Tranchant C, Bernard R, Plewniak F, Vicaire S, Levy N, Chelly J, Mandel JL, Biancalana V, Laporte J.

Acta Neuropathol 2012; 124(2):273-83

Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network.

Le Merrer J(1), Befort K, Gardon O, Filliol D, Darcq E, Dembele D, Becker JA, Kieffer BL.

Addict Biol 2012; 17(1):1-12

Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology.

Moutier E(1), Ye T, Choukrallah MA, Urban S, Osz J, Chatagnon A, Delacroix L, Langer D, Rochel N, Moras D, Benoit G, Davidson I.

J Biol Chem 2012; 287(31):26328-41

Samaritan myopathy, an ultimately benign congenital myopathy, is caused by a RYR1 mutation.

Böhm J(1), Leshinsky-Silver E, Vassilopoulos S, Le Gras S, Lerman-Sagie T, Ginzberg M, Jost B, Lev D, Laporte J.

Acta Neuropathol 2012; 124(4):575-81

Selective upregulation of lipid metabolism in skeletal muscle of foraging juvenile king penguins: an integrative study.

Teulier L(1), Dégletagne C, Rey B, Tornos J, Keime C, de Dinechin M, Raccurt M, Rouanet JL, Roussel D, Duchamp C.

Proc Biol Sci 2012; 279(1737):2464-72

Targeted high-throughput sequencing for diagnosis of genetically heterogeneous diseases: efficient mutation detection in Bardet-Biedl and Alstrom syndromes.

Redin C, Le Gras S, Mhamdi O, Geoffroy V, Stoetzel C, Vincent MC, Chiurazzi P, Lacombe D, Ouertani I, Petit F, Till M, Verloes A, Jost B, Chaabouni HB, Dollfus H, Mandel JL, Muller J.

J Med Genet 2012; 49(8):502-12

The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

Raveau M(1), Lignon JM, Nalesso V, Duchon A, Groner Y, Sharp AJ, Dembele D, Brault V, Herault Y.

PLoS Genet 2012; 8(5):e1002724

Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation.

Benhaddou A, Keime C, Ye T, Morlon A, Michel I, Jost B, Mengus G, Davidson I.

Cell Death Differ 2012; 19(2):220-31

A python module to normalize microarray data by the quantile adjustment method.

Baber I, Tamby JP, Manoukis NC, Sangaré D, Doumbia S, Traoré SF, Maiga MS, Dembélé D.

Infect Genet Evol 2011; 11(4):765-8

B cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupus.

Garaud JC(1), Schickel JN, Blaison G, Knapp AM, Dembele D, Ruer-Laventie J, Korganow AS, Martin T, Soulas-Sprauel P, Pasquali JL.

PLoS One 2011; 6(8):e23900

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

Strub T., Giuliano S., Ye T., Bonet C., Keime C., Kobi D., Le Gras S., Cormont M., Ballotti R., Bertolotto C., Davidson I.

Oncogene 2011; 30(20):2319-32

Genetic diversity, structure, gene flow and evolutionary relationships within the Sorghum bicolor wild-weedy-crop complex in a western African region.

Sagnard F(1), Deu M, Dembélé D, Leblois R, Touré L, Diakité M, Calatayud C, Vaksmann M, Bouchet S, Mallé Y, Togola S, Traoré PC.

Theor Appl Genet 2011; 123(7):1231-46

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

Fugier C., Klein A.F., Hammer C., Vassilopoulos S., Ivarsson Y., Toussaint A., Tosch V., Vignaud A., Ferry A., Messaddeq N., Kokunai Y., Tsuburaya R., de la Grange P., Dembele D., Francois V., Precigout G., Boulade-Ladame C., Hummel M.C., de Munain A.L., Sergeant N., Laquerriere A., Thibault C., Deryckere F., Auboeuf D., Garcia L., Zimmermann P., Udd B., Schoser B., Takahashi M.P., Nishino I., Bassez G., Laporte J., Furling D., Charlet-Berguerand N.

Nat Med 2011; 17(6):720-5

Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy

Rau F., Freyermuth F., Fugier C., Villemin J.P., Fischer M.C., Jost B., Dembele D., Gourdon G., Nicole A., Duboc D., Wahbi K., Day J.W., Fujimura H., Takahashi M.P., Auboeuf D., Dreumont N., Furling D., Charlet-Berguerand N.

Nat Struct Mol Biol 2011; 18(7):840-5

Molecular diagnosis of known recessive ataxias by homozygosity mapping with SNP arrays

H'Mida-Ben Brahim D., M'Zahem A., Assoum M., Bouhlal Y., Fattori F., Anheim M., Ali-Pacha L., Ferrat F., Chaouch M., Lagier-Tourenne C., Drouot N., Thibault C., Benhassine T., Sifi Y., Stoppa-Lyonnet D., N'Guyen K., Poujet J., Hamri A., Hentati F., Amouri R., Santorelli F.M., Tazir M., Koenig M.

J Neurol 2011; 258(1):56-67

Problematique de la prise en charge de linfarctus du myocarde a LHopital Desegou (Mali)

Bèye SA(1), Mallé KK, Wade KA, Djibo MD, Landrover RJ, Dembélé D, Coulibaly Y

Mali Med 2011; 26(3):45-7

Profiling target genes of FGF18 in the postnatal mouse lung: possible relevance for alveolar development.

Franco-Montoya ML, Boucherat O, Thibault C, Chailley-Heu B, Incitti R, Delacourt C, Bourbon JR.

Physiol Genomics 2011; 43(21):1226-40

seqMINER: an integrated ChIP-seq data interpretation platform.

Ye T(1), Krebs AR, Choukrallah MA, Keime C, Plewniak F, Davidson I, Tora L.

Nucleic Acids Res 2011; 39(6):e35

Transcriptome profile reveals AMPA receptor dysfunction in the hippocampus of the Rsk2-knockout mice, an animal model of Coffin-Lowry syndrome

Mehmood T., Schneider A., Sibillec J., Marques Pereira P., Pannetier S., Ammar M.R., Dembele D., Thibault-Carpentier C., Rouach N., Hanauer A.

Hum Genet 2011; 129(3):255-69

Tripartite Motif 24 (Trim24/Tif1{alpha}) Tumor Suppressor Protein Is a Novel Negative Regulator of Interferon (IFN)/Signal Transducers and Activators of Transcription (STAT) Signaling Pathway Acting through Retinoic Acid Receptor {alpha} (Rar{alpha}) Inhi

Tisserand J., Khetchoumian K., Thibault C., Dembele D., Chambon P., Losson R.

J Biol Chem 2011; 286(38):33369-79

A single acute pharmacological dose of gamma-hydroxybutyrate (GHB) modifies multiple gene expression patterns in rat hippocampus and frontal cortex.

Kemmel V, Klein C, Dembele D, Jost B, Taleb O, Aunis D, Mensah-Nyagan AG, Maitre M.

Physiol Genomics 2010; 41(2):146-160

A strategy for direct mapping and identification of mutations by whole-genome sequencing

Zuryn S., Le Gras S., Jamet K., Jarriault S.

Genetics 2010; 186(1):427-30

An adult tissue-specific stem cell molecular phenotype is activated in epithelial cancer stem cells and correlated to patient outcome

Hussenet T., Dembele D., Martinet N., Vignaud J.M., du Manoir S.

Cell Cycle 2010; 9(2):321-7

Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes

Kastner P., Chan S., Vogel W.K., Zhang L.J., Topark-Ngarm A., Golonzhka O., Jost B., Le Gras S., Gross M.K., Leid M.

Eur J Immunol 2010; 40(8):2143-54

Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells

Delacroix L., Moutier E., Altobelli G., Legras S., Poch O., Choukrallah M.A., Bertin I., Jost B., Davidson I.

Mol Cell Biol 2010; 30(1):231-44

Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells

Martianov I., Choukrallah M.A., Krebs A., Ye T., Legras S., Rijkers E., Van Ijcken W., Jost B., Sassone-Corsi P., Davidson I.

BMC Genomics 2010; 11():530

Cyclin K and cyclin D1b are oncogenic in myeloma cells

Marsaud V., Tchakarska G., Andrieux G., Liu J.M., Dembele D., Jost B., Wdzieczak-Bakala J., Renoir J.M., Sola B.

Mol Cancer 2010; 9():103

Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene

Kobi D., Steunou A.L., Dembele D., Legras S., Larue L., Nieto L., Davidson I.

Pigment Cell Melanoma Res 2010; 23(3):404-18

Identification of 28 novel mutations in the Bardet-Biedl syndrome genes: the burden of private mutations in an extensively heterogeneous disease

Muller J., Stoetzel C., Vincent M.C., Leitch C.C., Laurier V., Danse J.M., Helle S., Marion V., Bennouna-Greene V., Vicaire S., Megarbane A., Kaplan J., Drouin-Garraud V., Hamdani M., Sigaudy S., Francannet C., Roume J., Bitoun P., Goldenberg A., Philip N., Odent S., Green J., Cossee M., Davis E.E., Katsanis N., Bonneau D., Verloes A., Poch O., Mandel J.L., Dollfus H.

Hum Genet 2010; 127(5):583-93

Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique

Host L., Anglard P., Romieu P., Thibault C., Dembele D., Aunis D., Zwiller J.

J Neurochem 2010; 113(1):236-47

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

Jeannet R., Mastio J., Macias-Garcia A., Oravecz A., Ashworth T., Geimer Le Lay A.S., Jost B., Le Gras S., Ghysdael J., Gridley T., Honjo T., Radtke F., Aster J.C., Chan S., Kastner P.

Blood 2010; 116(25):5443-54

SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas

Hussenet T., Dali S., Exinger J., Monga B., Jost B., Dembele D., Martinet N., Thibault C., Huelsken J., Brambilla E., du Manoir S.

PLoS One 2010; 5(1):e8960

Confirmation of TFAP2A gene involvement in branchio-oculo-facial syndrome (BOFS) and report of temporal bone anomalies

Stoetzel C., Riehm S., Bennouna Greene V., Pelletier V., Vigneron J., Leheup B., Marion V., Helle S., Danse J.M., Thibault C., Moulinier L., Veillon F., Dollfus H.

Am J Med Genet A 2009; 149A(10):2141-6

Gene expression profile and response to trastuzumab-docetaxel-based treatment in breast carcinoma.

Végran F, Boidot R, Coudert B, Fumoleau P, Arnould L, Garnier J, Causeret S, Fraise J, Dembélé D, Lizard-Nacol S.

Br J Cancer 2009; 101(8):1357-64

ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency

Lagier-Tourenne C., Tazir M., Lopez L.C., Quinzii C.M., Assoum M., Drouot N., Busso C., Makri S., Ali-Pacha L., Benhassine T., Anheim M., Lynch D.R., Thibault C., Plewniak F., Bianchetti L., Tranchant C., Poch O., DiMauro S., Mandel J.L., Barros M.H., Hirano M., Koenig M.

Am J Hum Genet 2008; 82(3):661-72

Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells

Trouillas M., Saucourt C., Duval D., Gauthereau X., Thibault C., Dembele D., Feraud O., Menager J., Rallu M., Pradier L., Boeuf H.

Cell Death Differ 2008; 15(9):1450-9

Gene expression is altered in the lateral hypothalamus upon activation of the mu opioid receptor

Befort K., Filliol D., Darcq E., Ghate A., Matifas A., Lardenois A., Muller J., Thibault C., Dembele D., Poch O., Kieffer B.L.

Ann N Y Acad Sci 2008; 1129():175-84

Mu-opioid receptor activation induces transcriptional plasticity in the central extended amygdala

Befort K., Filliol D., Ghate A., Darcq E., Matifas A., Muller J., Lardenois A., Thibault C., Dembele D., Le Merrer J., Becker J.A., Poch O., Kieffer B.L.

Eur J Neurosci 2008; 27(11):2973-84

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

Robbins S.H., Walzer T., Dembele D., Thibault C., Defays A., Bessou G., Xu H., Vivier E., Sellars M., Pierre P., Sharp F.R., Chan S., Kastner P., Dalod M.

Genome Biol 2008; 9(1):R17

Retinoic acid induces TGFbeta-dependent autocrine fibroblast growth

Fadloun A., Kobi D., Delacroix L., Dembele D., Michel I., Lardenois A., Tisserand J., Losson R., Mengus G., Davidson I.

Oncogene 2008; 27(4):477-89

Transcriptome analysis identifies genes with enriched expression in the mouse central extended amygdala

Becker J.A., Befort K., Blad C., Filliol D., Ghate A., Dembele D., Thibault C., Koch M., Muller J., Lardenois A., Poch O., Kieffer B.L.

Neuroscience 2008; 156(4):950-965

Gene expression profiling in lung fibroblasts reveals new players in alveolarization.

Boucherat O, Franco-Montoya ML, Thibault C, Incitti R, Chailley-Heu B, Delacourt C, Bourbon JR.

Physiol Genomics 2007; 32(1):128-41

Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome

Stoetzel C., Muller J., Laurier V., Davis E.E., Zaghloul N.A., Vicaire S., Jacquelin C., Plewniak F., Leitch C.C., Sarda P., Hamel C., de Ravel T.J., Lewis R.A., Friederich E., Thibault C., Danse J.M., Verloes A., Bonneau D., Katsanis N., Poch O., Mandel J.L., Dollfus H.

Am J Hum Genet 2007; 80(1):1-11

Identification of novel striatal genes by expression profiling in adult mouse brain

Ghate A., Befort K., Becker J.A., Filliol D., Bole-Feysot C., Demebele D., Jost B., Koch M., Kieffer B.L.

Neuroscience 2007; 146(3):1182-1192

Loss of alpha6 integrins in keratinocytes leads to an increase in TGFbeta and AP1 signaling and in expression of differentiation genes

Rodius S., Indra G., Thibault C., Pfister V., Georges-Labouesse E.

J Cell Physiol 2007; 212(2):439-449

Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha

Khetchoumian K., Teletin M., Tisserand J., Mark M., Herquel B., Ignat M., Zucman-Rossi J., Cammas F., Lerouge T., Thibault C., Metzger D., Chambon P., Losson R.

Nat Genet 2007; 39(12):1500-1506

Systematic gene expression mapping clusters nuclear receptors according to their function in the brain

Gofflot F., Chartoire N., Vasseur L., Heikkinen S., Dembele D., Le Merrer J., Auwerx J.

Cell 2007; 131(2):405-18

The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis

Fadloun A., Kobi D., Pointud J.C., Indra A.K., Teletin M., Bole-Feysot C., Testoni B., Mantovani R., Metzger D., Mengus G., Davidson I.

Development 2007; 134(16):2947-58

An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes

Le Brigand K., Russell R., Moreilhon C., Rouillard J.M., Jost B., Amiot F., Magnone V., Bole-Feysot C., Rostagno P., Virolle V., Defamie V., Dessen P., Williams G., Lyons P., Rios G., Mari B., Gulari E., Kastner P., Gidrol X., Freeman T.C., Barbry P.

Nucleic Acids Res 2006; 34(12):e87

Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells

Duval D., Trouillas M., Thibault C., Dembele D., Diemunsch F., Reinhardt B., Mertz A.L., Dierich A., Boeuf H.

Cell Death Differ 2006; 13(4):564-75

BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus

Stoetzel C., Laurier V., Davis E.E., Muller J., Rix S., Badano J.L., Leitch C.C., Salem N., Chouery E., Corbani S., Jalk N., Vicaire S., Sarda P., Hamel C., Lacombe D., Holder M., Odent S., Holder S., Brooks A.S., Elcioglu N.H., Da Silva E., Rossillion B., Sigaudy S., de Ravel T.J., Alan Lewis R., Leheup B., Verloes A., Amati-Bonneau P., Megarbane A., Poch O., Bonneau D., Beales P.L., Mandel J.L., Katsanis N., Dollfus H.

Nat Genet 2006; 38(5):521-4

Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display

Carles A., Millon R., Cromer A., Ganguli G., Lemaire F., Young J., Wasylyk C., Muller D., Schultz I., Rabouel Y., Dembele D., Zhao C., Marchal P., Ducray C., Bracco L., Abecassis J., Poch O., Wasylyk B.

Oncogene 2006; 25(12):1821-31

Notch Activation Is an Early and Critical Event during T-Cell Leukemogenesis in Ikaros-Deficient Mice

Dumortier A., Jeannet R., Kirstetter P., Kleinmann E., Sellars M., Dos Santos N.R., Thibault C., Barths J., Ghysdael J., Punt J.A., Kastner P., Chan S.

Mol Cell Biol 2006; 26(1):209-20

Overlapping 3q28 amplifications in the COMA cell line and undifferentiated primary sarcoma

Hussenet T., Mallem N., Redon R., Jost B., Aurias A., du Manoir S.

Cancer Genet Cytogenet 2006; 169(2):102-13

Pitfalls of homozygosity mapping: an extended consanguineous Bardet-Biedl syndrome family with two mutant genes (BBS2, BBS10), three mutations, but no triallelism

Laurier V., Stoetzel C., Muller J., Thibault C., Corbani S., Jalkh N., Salem N., Chouery E., Poch O., Licaire S., Danse J.M., Amati-Bonneau P., Bonneau D., Megarbane A., Mandel J.L., Dollfus H.

Eur J Hum Genet 2006; 14(11):1195-203

Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program

Abou-Sleymane G., Chalmel F., Helmlinger D., Lardenois A., Thibault C., Weber C., Merienne K., Mandel J.L., Poch O., Devys D., Trottier Y.

Hum Mol Genet 2006; 15(5):691-703

Self-assembled small-molecule microarrays for protease screening and profiling

Urbina H.D., Debaene F., Jost B., Bole-Feysot C., Mason D.E., Kuzmic P., Harris J.L., Winssinger N.

Chembiochem 2006; 7(11):1790-7

Regulation of Rho signaling pathways in interleukin-2-stimulated human T-lymphocytes

Mzali R., Seguin L., Liot C., Auger A., Pacaud P., Loirand G., Thibault C., Pierre J., Bertoglio J.

Faseb J 2005; 19(13):1911-3

TAF4 inactivation in embryonic fibroblasts activates TGFbeta signalling and autocrine growth

Mengus G., Fadloun A., Kobi D., Thibault C., Perletti L., Michel I., Davidson I.

Embo J 2005; 24(15):2753-67

TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9

Frontini M., Soutoglou E., Argentini M., Bole-Feysot C., Jost B., Scheer E., Tora L.

Mol Cell Biol 2005; 25(11):4638-49

Using in vitro models for expression profiling studies on ethanol and drugs of abuse.

Thibault C, Hassan S, Miles M.

Addict Biol 2005; 10(1):53-62

Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis

Cromer A., Carles A., Millon R., Ganguli G., Chalmel F., Lemaire F., Young J., Dembele D., Thibault C., Muller D., Poch O., Abecassis J., Wasylyk B.

Oncogene 2004; 23(14):2484-98

Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood

Haddad R., Guardiola P., Izac B., Thibault C., Radich J., Delezoide A.L., Baillou C., Lemoine F.M., Gluckman J.C., Pflumio F., Canque B.

Blood 2004; 104(13):3918-26

Spatial and temporal expression of the zebrafish genome by large-scale in situ hybridization screening

Thisse B., Heyer V., Lux A., Alunni V., Degrave A., Seiliez I., Kirchner J., Parkhill J.P., Thisse C.

Methods Cell Biol 2004; 77():505-19

Fuzzy C-means method for clustering microarray data

Dembele D., Kastner P.

Bioinformatics 2003; 19(8):973-80

The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2

Pedron T., Thibault C., Sansonetti P.J.

J Biol Chem 2003; 278(36):33878-86

Amplicon mapping and transcriptional analysis pinpoint cyclin L as a candidate oncogene in head and neck cancer

Redon R., Hussenet T., Bour G., Caulee K., Jost B., Muller D., Abecassis J., du Manoir S.

Cancer Res 2002; 62(21):6211-7

Density of points clustering, application to transcriptomic data analysis

Wicker N., Dembele D., Raffelsberger W., Poch O.

Nucleic Acids Res 2002; 30(18):3992-4000

Quality indicators increase the reliability of microarray data

Raffelsberger W., Dembele D., Neubauer M.G., Gottardis M.M., Gronemeyer H.

Genomics 2002; 80(4):385-94

Complete sequence of the human RNA polymerase II largest subunit

Wintzerith M., Acker J., Vicaire S., Vigneron M., Kedinger C.

Nucleic Acids Res. 1992; 20():910

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