Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures.
Cell Rep 2019; 26(9):2477-2493
Deep RNA-Seq reveals miRNome differences in mammary tissue of lactating Holstein and Montbeliarde cows.
BMC Genomics 2019; 20(1):621
Genetic regulation of amphioxus somitogenesis informs the evolution of the vertebrate head mesoderm.
Nat Ecol Evol 2019; 3(8):1233-1240
Identification and expression of microRNAs in european eels Anguilla anguilla from two natural sites with different pollution levels.
Environ Pollut 2019; 250():274-283
Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice.
Front Psychiatry 2019; 9():726
RNA profiling of human testicular cells identifies syntenic lncRNAs associated with spermatogenesis.
Hum Reprod 2019; 34(7):1278-1290
Subclinical endometritis in dairy cattle is associated with distinct mRNA expression patterns in blood and endometrium.
PLoS One 2019; 14(8):e0220244
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
J Med Chem 2019; 62(3):1138-1166
A new genetically engineered mouse model of choroid plexus carcinoma.
Biochem Biophys Res Commun 2018; 496(2):568-574
Analysis of high-throughput biological data using their rank values.
Stat Methods Med Res 2018; 28(8):2276-2291
Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder.
Biol Psychiatry 2018; 84(4):239-252
Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription.
Hum Mol Genet 2018; 27(12):2171-2186
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies.
Eur J Med Chem 2018; 157():127-138
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.
EMBO Mol Med 2018; 10(11):e8587
Responses to climatic and pathogen threats differ in biodynamic and conventional vines.
Sci Rep 2018; 8(1):16857
Short- and long-term gene expression profiles induced by inhaled TiO2 nanostructured aerosol in rat lung.
Toxicol Appl Pharmacol 2018; 356(0):54-64
Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis.
Front Mol Neurosci 2018; 10():433
Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature.
Sci Rep 2017; 7():42875
Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression.
Plant Cell 2017; 29(7):1773-1793
B cells differentiate in Human thymus and express AIRE.
J Allergy Clin Immunol 2017; 139(3):1049-1052
Blepharocheilodontic syndrome is a CDH1 pathway-related disorder due to mutations in CDH1 and CTNND1.
Genet Med 2017; 19(9):1013-1021
Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation.
Mol Cell 2017; 68(6):1054-1066
Genome-wide Analysis of RARbeta Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.
Mol Neurobiol 2017; 54(5):3859-3878
Inhibition of beta-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis.
Sci Rep 2017; 7(1):5235
Intragenic FMR1 disease-causing variants: a significant mutational mechanism leading to Fragile-X syndrome.
Eur J Hum Genet 2017; 25(4):423-431
MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity.
Genome Biol 2017; 18(1):131
MITF-high and MITF-low cells and a novel subpopulation expressing genes of both cell states contribute to intra and inter-tumoral heterogeneity of primary melanoma.
Clin Cancer Res 2017; 23(22):7097-7107
Sphingolipid metabolism is dysregulated at transcriptomic and metabolic levels in the spinal cord of an animal model of amyotrophic lateral sclerosis.
Frontiers in Molecular Neuroscience 2017; ():
T Cell Zone Resident Macrophages Silently Dispose of Apoptotic Cells in the Lymph Node.
Immunity 2017; 47(2):349-362
TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.
PLoS Genet 2017; 13(2):e1006600
Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression.
J Cell Sci 2017; 130(8):1463-1474
The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility.
Genome Biol 2017; 18(1):114
A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement.
J Med Genet 2016; 53(2):98-110
Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes.
BMC Bioinformatics 2016; 17(1):462
Enterocyte Purge and Rapid Recovery Is a Resilience Reaction of the Gut Epithelium to Pore-Forming Toxin Attack.
Cell Host Microbe 2016; 20(6):716-730
Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.
Nat Commun 2016; 7():11063
Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids.
PLoS Genet 2016; 12(12):e1006512
Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons.
Proc Natl Acad Sci U S A 2016; 113(26):E3619-28
Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells.
Nature 2016; 530(7588):113-6
Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis.
J Virol 2016; 90(14):6387-400
Reduced DICER1 Expression Bestows Rheumatoid Arthritis Synoviocytes Proinflammatory Properties and Resistance to Apoptotic Stimuli.
Arthritis Rheumatol 2016; 68(8):1839-48
Reversal of Pathologic Lipid Accumulation in NPC1-Deficient Neurons by Drug-Promoted Release of LAMP1-Coated Lamellar Inclusions.
J Neurosci 2016; 36(30):8012-25
Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.
Nat Commun 2016; 7():11067
A Brn2-Zic1 axis specifies the neuronal fate of retinoic-acid-treated embryonic stem cells.
J Cell Sci 2015; 128(13):2303-18
Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.
PLoS Genet 2015; 11(10):e1005555
Circulating Human Eosinophils Share a Similar Transcriptional Profile in Asthma and Other Hypereosinophilic Disorders.
PLoS One 2015; 10(11):e0141740
Constitutive arsenite oxidase expression detected in arsenic-hypertolerant Pseudomonas xanthomarina S11.
Res Microbiol 2015; 166(3):205-14
Deletion of the App-Runx1 region in mice models human partial monosomy 21.
Dis Model Mech 2015; 8(6):623-34
Early adaptive response of the retina to a pro-diabetogenic diet: Impairment of cone response and gene expression changes in high-fructose fed rats.
Exp Eye Res 2015; 135():37-46
Endogenous siRNAs and piRNAs derived from transposable elements and genes in the malaria vector mosquito Anopheles gambiae.
BMC Genomics 2015; 16(1):278
Genome-Wide Mapping of Collier In Vivo Binding Sites Highlights Its Hierarchical Position in Different Transcription Regulatory Networks.
PLoS One 2015; 10(7):e0133387
Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2.
Nat Commun 2015; 6():8823
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.
Hum Mol Genet 2015; 24(12):3481-96
No evidence for generation of alternatively spliced isoforms from the mutated Trim24 allele lacking exon 4 in mouse liver.
J Hepatol 2015; 63(1):276-7
Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.
PLoS Genet 2015; 11(3):e1005062
Single-cell gene expression signatures reveal melanoma cell heterogeneity.
Oncogene 2015; 34(25):3251-63
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.
Elife 2015; 4():e06857
20 ans apres: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition.
Eur J Hum Genet 2014; 22(6):776-83
Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing.
J Med Genet 2014; 51(11):724-36
Fold change rank ordering statistics: a new method for detecting differentially expressed genes.
BMC Bioinformatics 2014; 15():14
Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts.
J Cell Sci 2014; 127(Pt 3):521-33
Interpreting and visualizing ChIP-seq data with the seqMINER software.
Methods Mol Biol 2014; 1150(Chap 8):141-52
Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation.
Elife 2014; 3():e02104
Phosphorylation of the retinoic acid receptor RARgamma2 is crucial for the neuronal differentiation of mouse embryonic stem cells.
J Cell Sci 2014; 127(PT 9):2095-2105
T-cell factor 4 and beta-catenin chromatin occupancies pattern zonal liver metabolism in mice.
Hepatology 2014; 59(6):2344-57
TAF4 Inactivation Reveals the 3 Dimensional Growth Promoting Activities of Collagen 6A3.
PLoS One 2014; 9(2):e87365
TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
Elife 2014; 3():e03613
The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response.
PLoS One 2014; 9(11):e113050
The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.
Sci Signal 2014; 7(317):ra28
Transcriptome-wide analysis of microRNA expression in the malaria mosquito Anopheles gambiae.
BMC Genomics 2014; 15():557
A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis.
Brief Bioinform 2013; 14(6):671-683
beta-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL.
Blood 2013; 122(5):694-704
Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA.
Nat Struct Mol Biol 2013; 20(3):332-8
Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome.
Eur J Hum Genet 2013; 21(6):637-42
Genetic analysis of the biosynthesis of 2-methoxy-3-isobutylpyrazine, a major grape-derived aroma compound impacting wine quality.
Plant Physiol 2013; 162(2):604-15
Genome Sequence of Halomonas sp. Strain A3H3, Isolated from Arsenic-Rich Marine Sediments.
Genome Announc 2013; 1(5):e00819-13
Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs.
Cell 2013; 153(4):812-27
Sequestration of DROSHA and DGCR8 by Expanded CGG RNA Repeats Alters MicroRNA Processing in Fragile X-Associated Tremor/Ataxia Syndrome.
Cell Rep 2013; 3(3):869-80
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.
Genome Res 2013; 23(10):1563-79
TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs.
Oncogene 2013; 32(39):4646-55
Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature
Arteriosclerosis, thrombosis, and vascular biology 2013; 33(1):76-86
Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling.
PLoS One 2013; 8(4):e62274
Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice.
PLoS One 2012; 7(5):e37710
Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells.
Nucleic Acids Res 2012; 40(1):270-83
Next generation sequencing for molecular diagnosis of neuromuscular diseases.
Acta Neuropathol 2012; 124(2):273-83
Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network.
Addict Biol 2012; 17(1):1-12
Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology.
J Biol Chem 2012; 287(31):26328-41
Samaritan myopathy, an ultimately benign congenital myopathy, is caused by a RYR1 mutation.
Acta Neuropathol 2012; 124(4):575-81
Selective upregulation of lipid metabolism in skeletal muscle of foraging juvenile king penguins: an integrative study.
Proc Biol Sci 2012; 279(1737):2464-72
Targeted high-throughput sequencing for diagnosis of genetically heterogeneous diseases: efficient mutation detection in Bardet-Biedl and Alstrom syndromes.
J Med Genet 2012; 49(8):502-12
The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.
PLoS Genet 2012; 8(5):e1002724
A python module to normalize microarray data by the quantile adjustment method.
Infect Genet Evol 2011; 11(4):765-8
B cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupus.
PLoS One 2011; 6(8):e23900
Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
Oncogene 2011; 30(20):2319-32
Genetic diversity, structure, gene flow and evolutionary relationships within the Sorghum bicolor wild-weedy-crop complex in a western African region.
Theor Appl Genet 2011; 123(7):1231-46
Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy
Nat Med 2011; 17(6):720-5
Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy
Nat Struct Mol Biol 2011; 18(7):840-5
Molecular diagnosis of known recessive ataxias by homozygosity mapping with SNP arrays
J Neurol 2011; 258(1):56-67
Problematique de la prise en charge de linfarctus du myocarde a LHopital Desegou (Mali)
Mali Med 2011; 26(3):45-7
Profiling target genes of FGF18 in the postnatal mouse lung: possible relevance for alveolar development.
Physiol Genomics 2011; 43(21):1226-40
Transcriptome profile reveals AMPA receptor dysfunction in the hippocampus of the Rsk2-knockout mice, an animal model of Coffin-Lowry syndrome
Hum Genet 2011; 129(3):255-69
A single acute pharmacological dose of gamma-hydroxybutyrate (GHB) modifies multiple gene expression patterns in rat hippocampus and frontal cortex.
Physiol Genomics 2010; 41(2):146-160
A strategy for direct mapping and identification of mutations by whole-genome sequencing
Genetics 2010; 186(1):427-30
An adult tissue-specific stem cell molecular phenotype is activated in epithelial cancer stem cells and correlated to patient outcome
Cell Cycle 2010; 9(2):321-7
Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes
Eur J Immunol 2010; 40(8):2143-54
Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells
Mol Cell Biol 2010; 30(1):231-44
Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells
BMC Genomics 2010; 11():530
Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene
Pigment Cell Melanoma Res 2010; 23(3):404-18
Identification of 28 novel mutations in the Bardet-Biedl syndrome genes: the burden of private mutations in an extensively heterogeneous disease
Hum Genet 2010; 127(5):583-93
Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique
J Neurochem 2010; 113(1):236-47
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
Blood 2010; 116(25):5443-54
Confirmation of TFAP2A gene involvement in branchio-oculo-facial syndrome (BOFS) and report of temporal bone anomalies
Am J Med Genet A 2009; 149A(10):2141-6
ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency
Am J Hum Genet 2008; 82(3):661-72
Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells
Cell Death Differ 2008; 15(9):1450-9
Gene expression is altered in the lateral hypothalamus upon activation of the mu opioid receptor
Ann N Y Acad Sci 2008; 1129():175-84
Mu-opioid receptor activation induces transcriptional plasticity in the central extended amygdala
Eur J Neurosci 2008; 27(11):2973-84
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling
Genome Biol 2008; 9(1):R17
Gene expression profiling in lung fibroblasts reveals new players in alveolarization.
Physiol Genomics 2007; 32(1):128-41
Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome
Am J Hum Genet 2007; 80(1):1-11
Identification of novel striatal genes by expression profiling in adult mouse brain
Neuroscience 2007; 146(3):1182-1192
Loss of alpha6 integrins in keratinocytes leads to an increase in TGFbeta and AP1 signaling and in expression of differentiation genes
J Cell Physiol 2007; 212(2):439-449
Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha
Nat Genet 2007; 39(12):1500-1506
Systematic gene expression mapping clusters nuclear receptors according to their function in the brain
Cell 2007; 131(2):405-18
An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes
Nucleic Acids Res 2006; 34(12):e87
Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells
Cell Death Differ 2006; 13(4):564-75
BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus
Nat Genet 2006; 38(5):521-4
Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display
Oncogene 2006; 25(12):1821-31
Notch Activation Is an Early and Critical Event during T-Cell Leukemogenesis in Ikaros-Deficient Mice
Mol Cell Biol 2006; 26(1):209-20
Overlapping 3q28 amplifications in the COMA cell line and undifferentiated primary sarcoma
Cancer Genet Cytogenet 2006; 169(2):102-13
Pitfalls of homozygosity mapping: an extended consanguineous Bardet-Biedl syndrome family with two mutant genes (BBS2, BBS10), three mutations, but no triallelism
Eur J Hum Genet 2006; 14(11):1195-203
Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program
Hum Mol Genet 2006; 15(5):691-703
Regulation of Rho signaling pathways in interleukin-2-stimulated human T-lymphocytes
Faseb J 2005; 19(13):1911-3
TAF4 inactivation in embryonic fibroblasts activates TGFbeta signalling and autocrine growth
Embo J 2005; 24(15):2753-67
TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9
Mol Cell Biol 2005; 25(11):4638-49
Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis
Oncogene 2004; 23(14):2484-98
Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood
Blood 2004; 104(13):3918-26
Amplicon mapping and transcriptional analysis pinpoint cyclin L as a candidate oncogene in head and neck cancer
Cancer Res 2002; 62(21):6211-7
Density of points clustering, application to transcriptomic data analysis
Nucleic Acids Res 2002; 30(18):3992-4000