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Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells.

Grunddal KV, Tonack S, Egerod KL, Thompson JJ, Petersen N, Engelstoft MS, Vagne C, Keime C, Gradwohl G, Offermanns S, Schwartz TW

Mol Metab 2021; 51():101231

Nutrigenomic analyses reveal miRNAs and mRNAs affected by feed restriction in the mammary gland of midlactation dairy cows.

Billa PA, Faulconnier Y, Ye T, Bourdon C, Pires JAA, Leroux C

PLoS One 2021; 16(4):e0248680

Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process.

Mimouni NEH, Paiva I, Barbotin AL, Timzoura FE, Plassard D, Le Gras S, Ternier G, Pigny P, Catteau-Jonard S, Simon V, Prevot V, Boutillier AL, Giacobini P

Cell Metab 2021; 33(3):513-530.e8

Radiosensitizing Pancreatic Cancer with PARP Inhibitor and Gemcitabine: An In Vivo and a Whole-Transcriptome Analysis after Proton or Photon Irradiation.

Waissi W, Nicol A, Jung M, Rousseau M, Jarnet D, Noel G, Burckel H

Cancers (Basel) 2021; 13(3):

Succinylation of H3K122 destabilizes nucleosomes and enhances transcription.

Zorro Shahidian L, Haas M, Le Gras S, Nitsch S, Mourão A, Geerlof A, Margueron R, Michaelis J, Daujat S, Schneider R

EMBO Rep 2021; 22(3):e51009

An Integrated Analysis of miRNA and Gene Expression Changes in Response to an Obesogenic Diet to Explore the Impact of Transgenerational Supplementation with Omega 3 Fatty Acids.

Corral-Jara KF, Cantini L, Poupin N, Ye T, Rigaudière JP, De Saint Vincent S, Pinel A, Morio B, Capel F

Nutrients 2020; 12(12):

Attitudes towards Genetic Information Delivered by High-Throughput Sequencing among Molecular Geneticists, Genetic Counselors, Medical Advisors and Students in France.

Titerlea V, Dembélé D, Mandel JL, Laporte J

Eur J Med Genet 2020; 63(4):103770

Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia.

Laurent AP, Siret A, Ignacimouttou C, Panchal K, Diop M, Jenni S, Tsai YC, Roos-Weil D, Aid Z, Prade N, Lagarde S, Plassard D, Pierron G, Daudigeos E, Lecluse Y, Droin N, Bornhauser BC, Cheung LC, Crispino JD, Gaudry M, Bernard OA, Macintyre E, Barin Bonnigal C, Kotecha RS, Geoerger B, Ballerini P, Bourquin JP, Delabesse E, Mercher T, Malinge S

Clin Cancer Res 2020; 26(13):3307-3318

µgreen-db: a reference database for the 23S rRNA gene of eukaryotic plastids and cyanobacteria.

Djemiel C, Plassard D, Terrat S, Crouzet O, Sauze J, Mondy S, Nowak V, Wingate L, Ogée J, Maron PA

Sci Rep 2020; 10(1):5915

Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3.

Burton A, Brochard V, Galan C, Ruiz-Morales ER, Rovira Q, Rodriguez-Terrones D, Kruse K, Le Gras S, Udayakumar VS, Chin HG, Eid A, Liu X, Wang C, Gao S, Pradhan S, Vaquerizas JM, Beaujean N, Jenuwein T, Torres-Padilla ME

Nat Cell Biol 2020; 22(7):767-778

Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma.

Rabé M(1), Dumont S(1)(2), Álvarez-Arenas A(3), Janati H(4), Belmonte-Beitia J(3), Calvo GF(3), Thibault-Carpentier C(5), Séry Q(1)(6), Chauvin C(1), Joalland N(1), Briand F(1), Blandin S(7), Scotet E(1), Pecqueur C(1), Clairambault J(4), Oliver L(1)(8), Perez-Garcia V(3), Nadaradjane A(1)(6), Cartron PF(1)(6), Gratas C(9)(10), Vallette FM(11)(12).

Cell Death Dis 2020; 11(1):19

Longitudinal transcriptomic analysis of altered pathways in a CHMP2B(intron5)-based model of ALS-FTD.

Waegaert R, Dirrig-Grosch S, Parisot F, Keime C, Henriques A, Loeffler JP, René F

Neurobiol Dis 2020; 136():104710

Meiosis Occurs Normally in the Fetal Ovary of Mice Lacking All Retinoic Acid Receptors

Nadège Vernet (1) , Diana Condrea (1) , Chloé Mayere (2) , Betty Féret (1) , Muriel Klopfenstein (1) , William Magnant (1) , Violaine Alunni (3) , Marius Telentin (1) (4) , Sirine Souali-Crespo (1) , Serge Nef (2) , Manuel Mark (1) (4), Norbert B Ghyselinck (1)

Science Advances 2020; ():

Novel IQCE variations confirm its role in postaxial polydactyly and cause ciliary defect phenotype in zebrafish.

Estrada-Cuzcano A, Etard C, Delvallée C, Stoetzel C, Schaefer E, Scheidecker S, Geoffroy V, Schneider A, Studer F, Mattioli F, Chennen K, Sigaudy S, Plassard D, Poch O, Piton A, Strahle U, Muller J, Dollfus H

Hum Mutat 2020; 41(1):240-254

TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage.

Yu C, Cvetesic N, Hisler V, Gupta K, Ye T, Gazdag E, Negroni L, Hajkova P, Berger I, Lenhard B, Müller F, Vincent SD, Tora L

Nat Commun 2020; 11(1):6439

Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma.

Fritah S, Muller A, Jiang W, Mitra R, Sarmini M, Dieterle M, Golebiewska A, Ye T, Van Dyck E, Herold-Mende C, Zhao Z, Azuaje F, Niclou SP

Cancers (Basel) 2020; 12(9):

An actin-based viscoplastic lock ensures progressive body-axis elongation

Alicia Lardennois 1 , Gabriella Pásti 2 , Teresa Ferraro 1 , Flora Llense 1 , Pierre Mahou 3 , Julien Pontabry 2 4 , David Rodriguez 2 , Samantha Kim 2 , Shoichiro Ono 5 , Emmanuel Beaurepaire 3 , Christelle Gally 2 , Michel Labouesse 6 7

Nature 2019; ():

Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures.

Merienne N(1), Meunier C(2), Schneider A(3), Seguin J(3), Nair SS(4), Rocher AB(5), Le Gras S(6), Keime C(6), Faull R(7), Pellerin L(8), Chatton JY(9), Neri C(4), Merienne K(3), Deglon N(10).

Cell Rep 2019; 26(9):2477-2493

Co-translational assembly of mammalian nuclear multisubunit complexes.

Kamenova I(1)(2)(3)(4), Mukherjee P(1)(2)(3)(4), Conic S(1)(2)(3)(4), Mueller F(5), El-Saafin F(1)(2)(3)(4), Bardot P(1)(2)(3)(4), Garnier JM(1)(2)(3)(4), Dembele D(1)(2)(3)(4), Capponi S(6), Timmers HTM(6), Vincent SD(1)(2)(3)(4), Tora L(7)(8)(9)(10).

Nat Commun 2019; 10(1):1740

Deep RNA-Seq reveals miRNome differences in mammary tissue of lactating Holstein and Montbeliarde cows.

Billa PA(1), Faulconnier Y(1), Ye T(2), Chervet M(3), Le Provost F(4), Pires JAA(1), Leroux C(5)(6).

BMC Genomics 2019; 20(1):621

Disrupting the IL-36 and IL-23/IL-17 loop underlies the efficacy of calcipotriol and corticosteroid therapy for psoriasis.

German B(1)(2)(3)(4), Wei R(1)(2)(3)(4), Hener P(1)(2)(3)(4), Martins C(5), Ye T(1)(2)(3)(4), Gottwick C(6), Yang J(6), Seneschal J(5), Boniface K(5), Li M(1)(2)(3)(4).

JCI Insight 2019; (0):0

Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor.

Carvalho K(1), Faivre E(1), Pietrowski MJ(2), Marques X(3), Gomez-Murcia V(1), Deleau A(1), Huin V(1), Hansen JN(2), Kozlov S(2), Danis C(1)(4), Temido-Ferreira M(5), Coelho JE(5), Meriaux C(1), Eddarkaoui S(1), Gras SL(6), Dumoulin M(7), Cellai L(1); NeuroCEB Brain Bank, Landrieu I(4), Chern Y(8), Hamdane M(1), Buee L(1), Boutillier AL(9), Levi S(3), Halle A(2)(10), Lopes LV(5), Blum D(1).

Brain 2019; (0):0

Genetic regulation of amphioxus somitogenesis informs the evolution of the vertebrate head mesoderm.

Aldea D(1), Subirana L(1), Keime C(2), Meister L(1), Maeso I(3), Marcellini S(4), Gomez-Skarmeta JL(3), Bertrand S(5), Escriva H(6).

Nat Ecol Evol 2019; 3(8):1233-1240

Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3-Mutated Gliomas Recreate the Patient Tumor Complexity.

Blandin AF(1), Durand A(1), Litzler M(1), Tripp A(1), Guerin E(1), Ruhland E(2), Obrecht A(3), Keime C(4), Fuchs Q(5), Reita D(1)(5), Lhermitte B(5)(6)(7), Coca A(8), Jones C(9), Rebel IL(5), Villa P(3), Namer IJ(3), Dontenwill M(5), Guenot D(1), Entz-Werle N(5)(10).

Cancers (Basel) 2019; (0):0

Identification and expression of microRNAs in european eels Anguilla anguilla from two natural sites with different pollution levels.

Bertucci A(1), Pierron F(2), Ye T(3), Gonzalez P(2), Couture P(4), Baudrimont M(2).

Environ Pollut 2019; 250():274-283

Interleukin-32 Contributes to Human Nonalcoholic Fatty Liver Disease and Insulin Resistance.

Dali-Youcef N(1)(2), Vix M(3), Costantino F(3), El-Saghire H(4), Lhermitte B(5), Callari C(3), D'Agostino J(3), Perretta S(3), Paveliu S(3), Gualtierotti M(3), Dumeny E(6), Oudot MA(4), Jaulin A(2), Dembele D(7), Zeisel MB(4), Tomasetto C(2), Baumert TF(4)(8), Doffoel M(8).

Hepatol Commun 2019; 3(9):1205-1220

In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.

Rossitto M(1), Ollivier M(1)(2), Déjardin S(1), Pruvost A(3), Brun C(4), Marchive C(1), Nguyen AL(3), Ghettas A(3), Keime C(5), de Massy B(4), Poulat F(1), Philibert P(1)(6), Boizet-Bonhoure B(7).

Commun Biol 2019; 2(1):310

In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.

Rossitto M(1), Ollivier M(1)(2), Dejardin S(1), Pruvost A(3), Brun C(4), Marchive C(1), Nguyen AL(3), Ghettas A(3), Keime C(5), de Massy B(4), Poulat F(1), Philibert P(1)(6), Boizet-Bonhoure B(1).

Commun Biol 2019; 2():310

Publisher Correction: An actin-based viscoplastic lock ensures progressive body-axis elongation.

Lardennois A(1), Pasti G(2), Ferraro T(1), Llense F(1), Mahou P(3), Pontabry J(2)(4), Rodriguez D(2), Kim S(2), Ono S(5), Beaurepaire E(3), Gally C(2), Labouesse M(6)(7).

Nature 2019; (0):0

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production.

Piccand J(1), Vagne C(1), Blot F(1), Meunier A(1), Beucher A(1), Strasser P(1), Lund ML(2), Ghimire S(1), Nivlet L(1), Lapp C(1), Petersen N(2), Engelstoft MS(2), Thibault-Carpentier C(1), Keime C(1), Correa SJ(1), Schreiber V(1), Molina N(1), Schwartz TW(2), De Arcangelis A(3), Gradwohl G(4).

Mol Metab 2019; 29():24-39

RNA profiling of human testicular cells identifies syntenic lncRNAs associated with spermatogenesis.

Rolland AD(1), Evrard B(1), Darde TA(1)(2), Le Beguec C(1), Le Bras Y(2), Bensalah K(3), Lavoue S(4), Jost B(5), Primig M(1), Dejucq-Rainsford N(1), Chalmel F(1), Jegou B(1).

Hum Reprod 2019; 34(7):1278-1290

Subclinical endometritis in dairy cattle is associated with distinct mRNA expression patterns in blood and endometrium.

Raliou M(1), Dembele D(2), Duvel A(3), Bolifraud P(1), Aubert J(4), Mary-Huard T(4), Rocha D(5), Piumi F(1), Mockly S(1), Heppelmann M(6), Dieuzy-Labaye I(7), Zieger P(8), G E Smith D(9), Schuberth HJ(3), Sheldon IM(10), Sandra O(1).

PLoS One 2019; 14(8):e0220244

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.

Vogerl K(1), Ong N(1), Senger J(2), Herp D(2), Schmidtkunz K(2), Marek M(3), Muller M(1), Bartel K(1), Shaik TB(3), Porter NJ(4), Robaa D(5), Christianson DW(4), Romier C(3), Sippl W(5), Jung M(2), Bracher F(1).

J Med Chem 2019; 62(3):1138-1166

Transitional B cells in quiescent SLE: An early checkpoint imprinted by IFN.

Dieudonne Y(1), Gies V(2), Guffroy A(3), Keime C(4), Bird AK(5), Liesveld J(6), Barnas JL(5), Poindron V(1), Douiri N(7), Soulas-Sprauel P(8), Martin T(3), Meffre E(9), Anolik JH(5), Korganow AS(10).

J Autoimmun 2019; 102(0):150-158

Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3.

Florian RT(1), Kraft F(2), Leitao E(1), Kaya S(1), Klebe S(3), Magnin E(4), van Rootselaar AF(5), Buratti J(6), Kuhnel T(1), Schroder C(1), Giesselmann S(2), Tschernoster N(7), Altmueller J(7), Lamiral A(4), Keren B(6), Nava C(6)(8), Bouteiller D(8), Forlani S(8), Jornea L(8), Kubica R(1), Ye T(9), Plassard D(9), Jost B(9), Meyer V(10), Deleuze JF(10), Delpu Y(11), Avarello MDM(11), Vijfhuizen LS(12), Rudolf G(9)(13), Hirsch E(13), Kroes T(14), Reif PS(15)(16), Rosenow F(15)(16), Ganos C(17), Vidailhet M(8)(18), Thivard L(18), Mathieu A(19), Bourgeron T(19), Kurth I(2), Rafehi H(20)(21)(22), Steenpass L(1), Horsthemke B(1); FAME consortium, LeGuern E(6)(8), Klein KM(15)(16)(23), Labauge P(24), Bennett MF(20)(21)(22), Bahlo M(20)(21), Gecz J(14)(25), Corbett MA(14), Tijssen MAJ(26), van den Maagdenberg AMJM(12)(27), Depienne C(28)(29)(30).

Nat Commun 2019; 10(1):4919

Analysis of high-throughput biological data using their rank values.

Dembele D(1).

Stat Methods Med Res 2018; 28(8):2276-2291

A new genetically engineered mouse model of choroid plexus carcinoma.

El Nagar S(1), Zindy F(2), Moens C(3), Martin L(1), Plassard D(4), Roussel MF(2), Lamonerie T(1), Billon N(5).

Biochem Biophys Res Commun 2018; 496(2):568-574

Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription.

El-Saafin F(1)(2)(3)(4), Curry C(5)(6), Ye T(1)(2)(3)(4), Garnier JM(1)(2)(3)(4), Kolb-Cheynel I(1)(2)(3)(4), Stierle M(1)(2)(3)(4), Downer NL(7), Dixon MP(7), Negroni L(1)(2)(3)(4), Berger I(8), Thomas T(7)(9), Voss AK(7)(9), Dobyns W(10)(11), Devys D(1)(2)(3)(4), Tora L(1)(2)(3)(4).

Hum Mol Genet 2018; 27(12):2171-2186

Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice.

Maduna T, Audouard E, Dembélé D, Mouzaoui N, Reiss D, Massotte D, Gaveriaux-Ruff C

Front Psychiatry 2018; 9():726

Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies.

Brindisi M(1), Senger J(2), Cavella C(1), Grillo A(1), Chemi G(1), Gemma S(1), Cucinella DM(1), Lamponi S(1), Sarno F(3), Iside C(3), Nebbioso A(3), Novellino E(4), Shaik TB(5), Romier C(5), Herp D(2), Jung M(2), Butini S(6), Campiani G(7), Altucci L(3), Brogi S(1).

Eur J Med Chem 2018; 157():127-138

Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.

Chatterjee S(1)(2), Cassel R(1)(2), Schneider-Anthony A(1)(2), Merienne K(1)(2), Cosquer B(1)(2), Tzeplaeff L(1)(2), Halder Sinha S(3), Kumar M(3), Chaturbedy P(4), Eswaramoorthy M(4), Le Gras S(5), Keime C(5), Bousiges O(1)(6), Dutar P(7), Petsophonsakul P(8), Rampon C(8), Cassel JC(1)(2), Buee L(9), Blum D(9), Kundu TK(10), Boutillier AL(11)(2).

EMBO Mol Med 2018; 10(11):e8587

Responses to climatic and pathogen threats differ in biodynamic and conventional vines.

Soustre-Gacougnolle I(1)(2), Lollier M(2), Schmitt C(1), Perrin M(1), Buvens E(1), Lallemand JF(3), Mermet M(1), Henaux M(1), Thibault-Carpentier C(4), Dembele D(4), Steyer D(5), Clayeux C(5), Moneyron A(6), Masson JE(7).

Sci Rep 2018; 8(1):16857

Short- and long-term gene expression profiles induced by inhaled TiO2 nanostructured aerosol in rat lung.

Chezeau L(1), Sebillaud S(2), Safar R(3), Seidel C(2), Dembele D(4), Lorcin M(2), Langlais C(2), Grossmann S(2), Nunge H(2), Michaux S(2), Schneider HDP(5), Rihn B(6), Joubert O(6), Binet S(2), Cosnier F(2), Gate L(7).

Toxicol Appl Pharmacol 2018; 356(0):54-64

Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis.

Henriques A(1)(2)(3), Croixmarie V(4), Bouscary A(1)(2), Mosbach A(1)(2), Keime C(5), Boursier-Neyret C(6), Walter B(6), Spedding M(3), Loeffler JP(1)(2).

Front Mol Neurosci 2018; 10():433

Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis.

Bayer T(1), Chakrabarti A(2), Lancelot J(3), Shaik TB(4), Hausmann K(1), Melesina J(1), Schmidtkunz K(2), Marek M(4), Erdmann F(1), Schmidt M(1), Robaa D(1), Romier C(4), Pierce RJ(3), Jung M(2), Sippl W(1).

ChemMedChem 2018; 13(15):1517-1529

Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature.

Le Gras S(1), Keime C(1), Anthony A(2,)(3), Lotz C(2,)(3), De Longprez L(4,)(5), Brouillet E(4,)(5), Cassel JC(2,)(3), Boutillier AL(2,)(3), Merienne K(2,)(3).

Sci Rep 2017; 7():42875

Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression.

Duc C(1), Benoit M(1)(2), Detourne G(1)(3), Simon L(1), Poulet A(1)(3), Jung M(4), Veluchamy A(5)(6), Latrasse D(5), Le Goff S(1), Cotterell S(1), Tatout C(1), Benhamed M(5)(6), Probst AV(7).

Plant Cell 2017; 29(7):1773-1793

B cells differentiate in Human thymus and express AIRE.

Gies V(1), Guffroy A(1), Danion F(1), Billaud P(2), Keime C(3), Fauny JD(4), Susini S(5), Soley A(4), Martin T(6), Pasquali JL(6), Gros F(7), Andre-Schmutz I(5), Soulas-Sprauel P(8), Korganow AS(9).

J Allergy Clin Immunol 2017; 139(3):1049-1052

Blepharocheilodontic syndrome is a CDH1 pathway-related disorder due to mutations in CDH1 and CTNND1.

Ghoumid J(1)(2)(3), Stichelbout M(1)(2), Jourdain AS(2)(4), Frenois F(1)(2), Lejeune-Dumoulin S(1), Alex-Cordier MP(5), Lebrun M(6), Guerreschi P(2)(3)(7), Duquennoy-Martinot V(2)(3)(7), Vinchon M(2)(3)(8), Ferri J(3)(9), Jung M(10), Vicaire S(10), Vanlerberghe C(1)(2)(3), Escande F(2)(4), Petit F(1)(2)(3), Manouvrier-Hanu S(1)(2)(3).

Genet Med 2017; 19(9):1013-1021

Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation.

Epanchintsev A(1), Costanzo F(1), Rauschendorf MA(1), Caputo M(2), Ye T(1), Donnio LM(1), Proietti-de-Santis L(2), Coin F(1), Laugel V(3), Egly JM(4).

Mol Cell 2017; 68(6):1054-1066

Combinatorial DNA methylation codes at repetitive elements.

Papin C(1), Ibrahim A(1), Gras SL(1), Velt A(1), Stoll I(1), Jost B(1), Menoni H(2), Bronner C(1), Dimitrov S(2), Hamiche A(1).

Genome Res 2017; 27(6):934-946

Genome-wide Analysis of RARbeta Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.

Niewiadomska-Cimicka A(1)(2)(3)(4)(5), Krzyzosiak A(1)(2)(3)(4)(5)(6), Ye T(1)(2)(3)(4), Podlesny-Drabiniok A(1)(2)(3)(4)(5), Dembele D(1)(2)(3)(4), Dolle P(1)(2)(3)(4)(5), Krezel W(7)(8)(9)(10)(11).

Mol Neurobiol 2017; 54(5):3859-3878

Histone propionylation is a mark of active chromatin.

Kebede AF(1)(2), Nieborak A(3), Shahidian LZ(3), Le Gras S(1), Richter F(2)(4), Gomez DA(3)(5), Baltissen MP(6), Meszaros G(1)(7)(8), Magliarelli HF(1), Taudt A(9)(10), Margueron R(11), Colome-Tatche M(9)(10)(12), Ricci R(1)(7)(8), Daujat S(1), Vermeulen M(6), Mittler G(2), Schneider R(1)(3)(13).

Nat Struct Mol Biol 2017; 24(12):1048-1056

Inhibition of beta-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis.

Henriques A(1)(2)(3), Huebecker M(4), Blasco H(5)(6), Keime C(7), Andres CR(5)(6), Corcia P(5)(8), Priestman DA(4), Platt FM(4), Spedding M(3), Loeffler JP(9)(10).

Sci Rep 2017; 7(1):5235

Intragenic FMR1 disease-causing variants: a significant mutational mechanism leading to Fragile-X syndrome.

Quartier A(1,)(2,)(3,)(4), Poquet H(5,)(6), Gilbert-Dussardier B(7), Rossi M(8), Casteleyn AS(9), Portes VD(10), Feger C(11), Nourisson E(11), Kuentz P(5,)(6), Redin C(1,)(2,)(3,)(4), Thevenon J(5,)(6), Mosca-Boidron AL(12), Callier P(12), Muller J(11,)(13), Lesca G(8), Huet F(6), Geoffroy V(13), El Chehadeh S(6,)(14), Jung M(1,)(2,)(3,)(4), Trojak B(15), Le Gras S(1,)(2,)(3,)(4), Lehalle D(5), Jost B(1,)(2,)(3,)(4), Maury S(14), Masurel A(6), Edery P(8), Thauvin-Robinet C(5,)(6), Gerard B(11), Mandel JL(1,)(2,)(3,)(4,)(11,)(16,)(17), Faivre L(5,)(6), Piton A(1,)(11).

Eur J Hum Genet 2017; 25(4):423-431

Macrophage production and activation are dependent on TRIM33.

Gallouet AS(1,)(2,)(3,)(4,)(5), Ferri F(1,)(2,)(3,)(4,)(5,)(6), Petit V(1,)(2,)(3,)(4,)(5), Parcelier A(1,)(2,)(3,)(4,)(5), Lewandowski D(1,)(2,)(3,)(4,)(5), Gault N(1,)(2,)(3,)(4,)(5), Barroca V(1,)(2,)(3,)(4,)(5), Le Gras S(6), Soler E(1,)(2,)(3,)(4,)(7), Grosveld F(7), Davidson I(6), Romeo PH(1,)(2,)(3,)(4,)(5).

Oncotarget 2017; 8(3):5111-5122

MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity.

Latrasse D(1), Jegu T(1), Li H(2), de Zelicourt A(3), Raynaud C(1), Legras S(4), Gust A(5), Samajova O(6), Veluchamy A(3), Rayapuram N(3), Ramirez-Prado JS(3), Kulikova O(2), Colcombet J(1), Bigeard J(1), Genot B(1), Bisseling T(2), Benhamed M(1)(3), Hirt H(7)(8).

Genome Biol 2017; 18(1):131

MITF-high and MITF-low cells and a novel subpopulation expressing genes of both cell states contribute to intra and inter-tumoral heterogeneity of primary melanoma.

Ennen M(1), Keime C(1), Gambi G(1), Kieny A(2), Coassolo S(2), Thibault-Carpentier C(1), Margerin-Schaller F(3), Davidson G(1), Vagne C(4), Lipsker D(5), Davidson I(6).

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Cell Host Microbe 2016; 20(6):716-730

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Nature 2016; 530(7588):113-6

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J Virol 2016; 90(14):6387-400

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BMC Genomics 2015; 16(1):278

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Hum Mol Genet 2015; 24(12):3481-96

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J Hepatol 2015; 63(1):276-7

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Oncogene 2015; 34(25):3251-63

Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells.

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Epigenetics Chromatin 2015; 8():45

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.

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Ultradeep sequencing in the therapeutic management of HIV-1 infection at treatment initiation.

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Eur J Hum Genet 2014; 22(6):776-83

Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing

Full text links full-text provider logo Actions Favorites Share Page navigation Title & authors Abstract Figures Similar articles Cited by References Publication types MeSH terms LinkOut - more resources J Med Genet . 2014 Nov;51(11):724-36. doi: 10.1136/jmedgenet-2014-102554. Epub 2014 Aug 28. Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing Claire Redin 1 , Bénédicte Gérard 2 , Julia Lauer 2 , Yvan Herenger 2 , Jean Muller 3 , Angélique Quartier 1 , Alice Masurel-Paulet 4 , Marjolaine Willems 5 , Gaétan Lesca 6 , Salima El-Chehadeh 4 , Stéphanie Le Gras 7 , Serge Vicaire 7 , Muriel Philipps 7 , Michaël Dumas 7 , Véronique Geoffroy 8 , Claire Feger 7 , Nicolas Haumesser 1 , Yves Alembik 9 , Magalie Barth 10 , Dominique Bonneau 10 , Estelle Colin 10 , Hélène Dollfus 11 , Bérénice Doray 9 , Marie-Ange Delrue 12 , Valérie Drouin-Garraud 13 , Elisabeth Flori 9 , Mélanie Fradin 14 , Christine Francannet 15 , Alice Goldenberg 13 , Serge Lumbroso 16 , Michèle Mathieu-Dramard 17 , Dominique Martin-Coignard 18 , Didier Lacombe 12 , Gilles Morin 17 , Anne Polge 16 , Sylvie Sukno 19 , Christel Thauvin-Robinet 4 , Julien Thevenon 4 , Martine Doco-Fenzy 20 , David Genevieve 5 , Pierre Sarda 5 , Patrick Edery 6 , Bertrand Isidor 21 , Bernard Jost 7 , Laurence Olivier-Faivre 4 , Jean-Louis Mandel 22 , Amélie Piton 1

Journal of Medical genetics 2014; ():

Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing

Claire Redin 1 , Bénédicte Gérard 2 , Julia Lauer 2 , Yvan Herenger 2 , Jean Muller 3 , Angélique Quartier 1 , Alice Masurel-Paulet 4 , Marjolaine Willems 5 , Gaétan Lesca 6 , Salima El-Chehadeh 4 , Stéphanie Le Gras 7 , Serge Vicaire 7 , Muriel Philipps 7 , Michaël Dumas 7 , Véronique Geoffroy 8 , Claire Feger 7 , Nicolas Haumesser 1 , Yves Alembik 9 , Magalie Barth 10 , Dominique Bonneau 10 , Estelle Colin 10 , Hélène Dollfus 11 , Bérénice Doray 9 , Marie-Ange Delrue 12 , Valérie Drouin-Garraud 13 , Elisabeth Flori 9 , Mélanie Fradin 14 , Christine Francannet 15 , Alice Goldenberg 13 , Serge Lumbroso 16 , Michèle Mathieu-Dramard 17 , Dominique Martin-Coignard 18 , Didier Lacombe 12 , Gilles Morin 17 , Anne Polge 16 , Sylvie Sukno 19 , Christel Thauvin-Robinet 4 , Julien Thevenon 4 , Martine Doco-Fenzy 20 , David Genevieve 5 , Pierre Sarda 5 , Patrick Edery 6 , Bertrand Isidor 21 , Bernard Jost 7 , Laurence Olivier-Faivre 4 , Jean-Louis Mandel 22 , Amélie Piton 1

Journal of Medical genetics 2014; ():

Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing.

Redin C(1), Gérard B(2), Lauer J(2), Herenger Y(2), Muller J(3), Quartier A(1), Masurel-Paulet A(4), Willems M(5), Lesca G(6), El-Chehadeh S(4), Le Gras S(7), Vicaire S(7), Philipps M(7), Dumas M(7), Geoffroy V(8), Feger C(7), Haumesser N(1), Alembik Y(9), Barth M(10), Bonneau D(10), Colin E(10), Dollfus H(11), Doray B(9), Delrue MA(12), Drouin-Garraud V(13), Flori E(9), Fradin M(14), Francannet C(15), Goldenberg A(13), Lumbroso S(16), Mathieu-Dramard M(17), Martin-Coignard D(18), Lacombe D(12), Morin G(17), Polge A(16), Sukno S(19), Thauvin-Robinet C(4), Thevenon J(4), Doco-Fenzy M(20), Genevieve D(5), Sarda P(5), Edery P(6), Isidor B(21), Jost B(7), Olivier-Faivre L(4), Mandel JL(22), Piton A(1).

J Med Genet 2014; 51(11):724-36

Fold change rank ordering statistics: a new method for detecting differentially expressed genes.

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BMC Bioinformatics 2014; 15():14

Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts.

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J Cell Sci 2014; 127(Pt 3):521-33

Interpreting and visualizing ChIP-seq data with the seqMINER software.

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Methods Mol Biol 2014; 1150(Chap 8):141-52

Phosphorylation of the retinoic acid receptor RARgamma2 is crucial for the neuronal differentiation of mouse embryonic stem cells.

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J Cell Sci 2014; 127(PT 9):2095-2105

Rfx6 maintains the functional identity of adult pancreatic beta cells.

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Cell Rep 2014; 9(6):2219-32

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

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TAF4 Inactivation Reveals the 3 Dimensional Growth Promoting Activities of Collagen 6A3.

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PLoS One 2014; 9(2):e87365

T-cell factor 4 and beta-catenin chromatin occupancies pattern zonal liver metabolism in mice.

Gougelet A(1), Torre C, Veber P, Sartor C, Bachelot L, Denechaud PD, Godard C, Moldes M, Burnol AF, Dubuquoy C, Terris B, Guillonneau F, Ye T, Schwarz M, Braeuning A, Perret C, Colnot S.

Hepatology 2014; 59(6):2344-57

The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response.

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PLoS One 2014; 9(11):e113050

The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.

Geimer Le Lay AS(1), Oravecz A, Mastio J, Jung C, Marchal P, Ebel C, Dembélé D, Jost B, Le Gras S, Thibault C, Borggrefe T, Kastner P, Chan S.

Sci Signal 2014; 7(317):ra28

Transcriptome-wide analysis of microRNA expression in the malaria mosquito Anopheles gambiae.

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BMC Genomics 2014; 15():557

UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells.

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A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis.

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beta-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL.

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Blood 2013; 122(5):694-704

Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA.

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Nat Struct Mol Biol 2013; 20(3):332-8

Genetic analysis of the biosynthesis of 2-methoxy-3-isobutylpyrazine, a major grape-derived aroma compound impacting wine quality.

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Plant Physiol 2013; 162(2):604-15

Genome Sequence of Halomonas sp. Strain A3H3, Isolated from Arsenic-Rich Marine Sediments.

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Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs.

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Cell 2013; 153(4):812-27

Molars and incisors: show your microarray IDs.

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Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.

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Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature

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PLoS One 2012; 7(5):e37710

Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells.

Carrière L, Graziani S, Alibert O, Ghavi-Helm Y, Boussouar F, Humbertclaude H, Jounier S, Aude JC, Keime C, Murvai J, Foglio M, Gut M, Gut I, Lathrop M, Soutourina J, Gérard M, Werner M.

Nucleic Acids Res 2012; 40(1):270-83

Next generation sequencing for molecular diagnosis of neuromuscular diseases.

Vasli N, Böhm J, Le Gras S, Muller J, Pizot C, Jost B, Echaniz-Laguna A, Laugel V, Tranchant C, Bernard R, Plewniak F, Vicaire S, Levy N, Chelly J, Mandel JL, Biancalana V, Laporte J.

Acta Neuropathol 2012; 124(2):273-83

Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network.

Le Merrer J(1), Befort K, Gardon O, Filliol D, Darcq E, Dembele D, Becker JA, Kieffer BL.

Addict Biol 2012; 17(1):1-12

Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology.

Moutier E(1), Ye T, Choukrallah MA, Urban S, Osz J, Chatagnon A, Delacroix L, Langer D, Rochel N, Moras D, Benoit G, Davidson I.

J Biol Chem 2012; 287(31):26328-41

Samaritan myopathy, an ultimately benign congenital myopathy, is caused by a RYR1 mutation.

Böhm J(1), Leshinsky-Silver E, Vassilopoulos S, Le Gras S, Lerman-Sagie T, Ginzberg M, Jost B, Lev D, Laporte J.

Acta Neuropathol 2012; 124(4):575-81

Selective upregulation of lipid metabolism in skeletal muscle of foraging juvenile king penguins: an integrative study.

Teulier L(1), Dégletagne C, Rey B, Tornos J, Keime C, de Dinechin M, Raccurt M, Rouanet JL, Roussel D, Duchamp C.

Proc Biol Sci 2012; 279(1737):2464-72

Targeted high-throughput sequencing for diagnosis of genetically heterogeneous diseases: efficient mutation detection in Bardet-Biedl and Alstrom syndromes.

Redin C, Le Gras S, Mhamdi O, Geoffroy V, Stoetzel C, Vincent MC, Chiurazzi P, Lacombe D, Ouertani I, Petit F, Till M, Verloes A, Jost B, Chaabouni HB, Dollfus H, Mandel JL, Muller J.

J Med Genet 2012; 49(8):502-12

The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

Raveau M(1), Lignon JM, Nalesso V, Duchon A, Groner Y, Sharp AJ, Dembele D, Brault V, Herault Y.

PLoS Genet 2012; 8(5):e1002724

Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation.

Benhaddou A, Keime C, Ye T, Morlon A, Michel I, Jost B, Mengus G, Davidson I.

Cell Death Differ 2012; 19(2):220-31

A python module to normalize microarray data by the quantile adjustment method.

Baber I, Tamby JP, Manoukis NC, Sangaré D, Doumbia S, Traoré SF, Maiga MS, Dembélé D.

Infect Genet Evol 2011; 11(4):765-8

B cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupus.

Garaud JC(1), Schickel JN, Blaison G, Knapp AM, Dembele D, Ruer-Laventie J, Korganow AS, Martin T, Soulas-Sprauel P, Pasquali JL.

PLoS One 2011; 6(8):e23900

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

Strub T., Giuliano S., Ye T., Bonet C., Keime C., Kobi D., Le Gras S., Cormont M., Ballotti R., Bertolotto C., Davidson I.

Oncogene 2011; 30(20):2319-32

Genetic diversity, structure, gene flow and evolutionary relationships within the Sorghum bicolor wild-weedy-crop complex in a western African region.

Sagnard F(1), Deu M, Dembélé D, Leblois R, Touré L, Diakité M, Calatayud C, Vaksmann M, Bouchet S, Mallé Y, Togola S, Traoré PC.

Theor Appl Genet 2011; 123(7):1231-46

Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy

Rau F., Freyermuth F., Fugier C., Villemin J.P., Fischer M.C., Jost B., Dembele D., Gourdon G., Nicole A., Duboc D., Wahbi K., Day J.W., Fujimura H., Takahashi M.P., Auboeuf D., Dreumont N., Furling D., Charlet-Berguerand N.

Nat Struct Mol Biol 2011; 18(7):840-5

Molecular diagnosis of known recessive ataxias by homozygosity mapping with SNP arrays

H'Mida-Ben Brahim D., M'Zahem A., Assoum M., Bouhlal Y., Fattori F., Anheim M., Ali-Pacha L., Ferrat F., Chaouch M., Lagier-Tourenne C., Drouot N., Thibault C., Benhassine T., Sifi Y., Stoppa-Lyonnet D., N'Guyen K., Poujet J., Hamri A., Hentati F., Amouri R., Santorelli F.M., Tazir M., Koenig M.

J Neurol 2011; 258(1):56-67

Problematique de la prise en charge de linfarctus du myocarde a LHopital Desegou (Mali)

Bèye SA(1), Mallé KK, Wade KA, Djibo MD, Landrover RJ, Dembélé D, Coulibaly Y

Mali Med 2011; 26(3):45-7

Profiling target genes of FGF18 in the postnatal mouse lung: possible relevance for alveolar development.

Franco-Montoya ML, Boucherat O, Thibault C, Chailley-Heu B, Incitti R, Delacourt C, Bourbon JR.

Physiol Genomics 2011; 43(21):1226-40

seqMINER: an integrated ChIP-seq data interpretation platform.

Ye T(1), Krebs AR, Choukrallah MA, Keime C, Plewniak F, Davidson I, Tora L.

Nucleic Acids Res 2011; 39(6):e35

Transcriptome profile reveals AMPA receptor dysfunction in the hippocampus of the Rsk2-knockout mice, an animal model of Coffin-Lowry syndrome

Mehmood T., Schneider A., Sibillec J., Marques Pereira P., Pannetier S., Ammar M.R., Dembele D., Thibault-Carpentier C., Rouach N., Hanauer A.

Hum Genet 2011; 129(3):255-69

Tripartite Motif 24 (Trim24/Tif1{alpha}) Tumor Suppressor Protein Is a Novel Negative Regulator of Interferon (IFN)/Signal Transducers and Activators of Transcription (STAT) Signaling Pathway Acting through Retinoic Acid Receptor {alpha} (Rar{alpha}) Inhi

Tisserand J., Khetchoumian K., Thibault C., Dembele D., Chambon P., Losson R.

J Biol Chem 2011; 286(38):33369-79

An adult tissue-specific stem cell molecular phenotype is activated in epithelial cancer stem cells and correlated to patient outcome

Hussenet T., Dembele D., Martinet N., Vignaud J.M., du Manoir S.

Cell Cycle 2010; 9(2):321-7

A single acute pharmacological dose of gamma-hydroxybutyrate (GHB) modifies multiple gene expression patterns in rat hippocampus and frontal cortex.

Kemmel V, Klein C, Dembele D, Jost B, Taleb O, Aunis D, Mensah-Nyagan AG, Maitre M.

Physiol Genomics 2010; 41(2):146-160

A strategy for direct mapping and identification of mutations by whole-genome sequencing

Zuryn S., Le Gras S., Jamet K., Jarriault S.

Genetics 2010; 186(1):427-30

Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes

Kastner P., Chan S., Vogel W.K., Zhang L.J., Topark-Ngarm A., Golonzhka O., Jost B., Le Gras S., Gross M.K., Leid M.

Eur J Immunol 2010; 40(8):2143-54

Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells

Delacroix L., Moutier E., Altobelli G., Legras S., Poch O., Choukrallah M.A., Bertin I., Jost B., Davidson I.

Mol Cell Biol 2010; 30(1):231-44

Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells

Martianov I., Choukrallah M.A., Krebs A., Ye T., Legras S., Rijkers E., Van Ijcken W., Jost B., Sassone-Corsi P., Davidson I.

BMC Genomics 2010; 11():530

Cyclin K and cyclin D1b are oncogenic in myeloma cells

Marsaud V., Tchakarska G., Andrieux G., Liu J.M., Dembele D., Jost B., Wdzieczak-Bakala J., Renoir J.M., Sola B.

Mol Cancer 2010; 9():103

Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene

Kobi D., Steunou A.L., Dembele D., Legras S., Larue L., Nieto L., Davidson I.

Pigment Cell Melanoma Res 2010; 23(3):404-18

Identification of 28 novel mutations in the Bardet-Biedl syndrome genes: the burden of private mutations in an extensively heterogeneous disease

Muller J., Stoetzel C., Vincent M.C., Leitch C.C., Laurier V., Danse J.M., Helle S., Marion V., Bennouna-Greene V., Vicaire S., Megarbane A., Kaplan J., Drouin-Garraud V., Hamdani M., Sigaudy S., Francannet C., Roume J., Bitoun P., Goldenberg A., Philip N., Odent S., Green J., Cossee M., Davis E.E., Katsanis N., Bonneau D., Verloes A., Poch O., Mandel J.L., Dollfus H.

Hum Genet 2010; 127(5):583-93

Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique

Host L., Anglard P., Romieu P., Thibault C., Dembele D., Aunis D., Zwiller J.

J Neurochem 2010; 113(1):236-47

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

Jeannet R., Mastio J., Macias-Garcia A., Oravecz A., Ashworth T., Geimer Le Lay A.S., Jost B., Le Gras S., Ghysdael J., Gridley T., Honjo T., Radtke F., Aster J.C., Chan S., Kastner P.

Blood 2010; 116(25):5443-54

SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas

Hussenet T., Dali S., Exinger J., Monga B., Jost B., Dembele D., Martinet N., Thibault C., Huelsken J., Brambilla E., du Manoir S.

PLoS One 2010; 5(1):e8960

Confirmation of TFAP2A gene involvement in branchio-oculo-facial syndrome (BOFS) and report of temporal bone anomalies

Stoetzel C., Riehm S., Bennouna Greene V., Pelletier V., Vigneron J., Leheup B., Marion V., Helle S., Danse J.M., Thibault C., Moulinier L., Veillon F., Dollfus H.

Am J Med Genet A 2009; 149A(10):2141-6

Gene expression profile and response to trastuzumab-docetaxel-based treatment in breast carcinoma.

Végran F, Boidot R, Coudert B, Fumoleau P, Arnould L, Garnier J, Causeret S, Fraise J, Dembélé D, Lizard-Nacol S.

Br J Cancer 2009; 101(8):1357-64

ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency

Lagier-Tourenne C., Tazir M., Lopez L.C., Quinzii C.M., Assoum M., Drouot N., Busso C., Makri S., Ali-Pacha L., Benhassine T., Anheim M., Lynch D.R., Thibault C., Plewniak F., Bianchetti L., Tranchant C., Poch O., DiMauro S., Mandel J.L., Barros M.H., Hirano M., Koenig M.

Am J Hum Genet 2008; 82(3):661-72

Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells

Trouillas M., Saucourt C., Duval D., Gauthereau X., Thibault C., Dembele D., Feraud O., Menager J., Rallu M., Pradier L., Boeuf H.

Cell Death Differ 2008; 15(9):1450-9

Gene expression is altered in the lateral hypothalamus upon activation of the mu opioid receptor

Befort K., Filliol D., Darcq E., Ghate A., Matifas A., Lardenois A., Muller J., Thibault C., Dembele D., Poch O., Kieffer B.L.

Ann N Y Acad Sci 2008; 1129():175-84

Mu-opioid receptor activation induces transcriptional plasticity in the central extended amygdala

Befort K., Filliol D., Ghate A., Darcq E., Matifas A., Muller J., Lardenois A., Thibault C., Dembele D., Le Merrer J., Becker J.A., Poch O., Kieffer B.L.

Eur J Neurosci 2008; 27(11):2973-84

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

Robbins S.H., Walzer T., Dembele D., Thibault C., Defays A., Bessou G., Xu H., Vivier E., Sellars M., Pierre P., Sharp F.R., Chan S., Kastner P., Dalod M.

Genome Biol 2008; 9(1):R17

Retinoic acid induces TGFbeta-dependent autocrine fibroblast growth

Fadloun A., Kobi D., Delacroix L., Dembele D., Michel I., Lardenois A., Tisserand J., Losson R., Mengus G., Davidson I.

Oncogene 2008; 27(4):477-89

SQUAT: A web tool to mine human, murine and avian SAGE data.

Leyritz J, Schicklin S, Blachon S, Keime C, Robardet C, Boulicaut JF, Besson J, Pensa RG, Gandrillon O.

BMC Bioinformatics 2008; 9():378

Transcriptome analysis identifies genes with enriched expression in the mouse central extended amygdala

Becker J.A., Befort K., Blad C., Filliol D., Ghate A., Dembele D., Thibault C., Koch M., Muller J., Lardenois A., Poch O., Kieffer B.L.

Neuroscience 2008; 156(4):950-965

Gene expression profiling in lung fibroblasts reveals new players in alveolarization.

Boucherat O, Franco-Montoya ML, Thibault C, Incitti R, Chailley-Heu B, Delacourt C, Bourbon JR.

Physiol Genomics 2007; 32(1):128-41

Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome

Stoetzel C., Muller J., Laurier V., Davis E.E., Zaghloul N.A., Vicaire S., Jacquelin C., Plewniak F., Leitch C.C., Sarda P., Hamel C., de Ravel T.J., Lewis R.A., Friederich E., Thibault C., Danse J.M., Verloes A., Bonneau D., Katsanis N., Poch O., Mandel J.L., Dollfus H.

Am J Hum Genet 2007; 80(1):1-11

Identification of novel striatal genes by expression profiling in adult mouse brain

Ghate A., Befort K., Becker J.A., Filliol D., Bole-Feysot C., Demebele D., Jost B., Koch M., Kieffer B.L.

Neuroscience 2007; 146(3):1182-1192

Loss of alpha6 integrins in keratinocytes leads to an increase in TGFbeta and AP1 signaling and in expression of differentiation genes

Rodius S., Indra G., Thibault C., Pfister V., Georges-Labouesse E.

J Cell Physiol 2007; 212(2):439-449

Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha

Khetchoumian K., Teletin M., Tisserand J., Mark M., Herquel B., Ignat M., Zucman-Rossi J., Cammas F., Lerouge T., Thibault C., Metzger D., Chambon P., Losson R.

Nat Genet 2007; 39(12):1500-1506

Systematic gene expression mapping clusters nuclear receptors according to their function in the brain

Gofflot F., Chartoire N., Vasseur L., Heikkinen S., Dembele D., Le Merrer J., Auwerx J.

Cell 2007; 131(2):405-18

The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis

Fadloun A., Kobi D., Pointud J.C., Indra A.K., Teletin M., Bole-Feysot C., Testoni B., Mantovani R., Metzger D., Mengus G., Davidson I.

Development 2007; 134(16):2947-58

An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes

Le Brigand K., Russell R., Moreilhon C., Rouillard J.M., Jost B., Amiot F., Magnone V., Bole-Feysot C., Rostagno P., Virolle V., Defamie V., Dessen P., Williams G., Lyons P., Rios G., Mari B., Gulari E., Kastner P., Gidrol X., Freeman T.C., Barbry P.

Nucleic Acids Res 2006; 34(12):e87

Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells

Duval D., Trouillas M., Thibault C., Dembele D., Diemunsch F., Reinhardt B., Mertz A.L., Dierich A., Boeuf H.

Cell Death Differ 2006; 13(4):564-75

BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus

Stoetzel C., Laurier V., Davis E.E., Muller J., Rix S., Badano J.L., Leitch C.C., Salem N., Chouery E., Corbani S., Jalk N., Vicaire S., Sarda P., Hamel C., Lacombe D., Holder M., Odent S., Holder S., Brooks A.S., Elcioglu N.H., Da Silva E., Rossillion B., Sigaudy S., de Ravel T.J., Alan Lewis R., Leheup B., Verloes A., Amati-Bonneau P., Megarbane A., Poch O., Bonneau D., Beales P.L., Mandel J.L., Katsanis N., Dollfus H.

Nat Genet 2006; 38(5):521-4

Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display

Carles A., Millon R., Cromer A., Ganguli G., Lemaire F., Young J., Wasylyk C., Muller D., Schultz I., Rabouel Y., Dembele D., Zhao C., Marchal P., Ducray C., Bracco L., Abecassis J., Poch O., Wasylyk B.

Oncogene 2006; 25(12):1821-31

Notch Activation Is an Early and Critical Event during T-Cell Leukemogenesis in Ikaros-Deficient Mice

Dumortier A., Jeannet R., Kirstetter P., Kleinmann E., Sellars M., Dos Santos N.R., Thibault C., Barths J., Ghysdael J., Punt J.A., Kastner P., Chan S.

Mol Cell Biol 2006; 26(1):209-20

Overlapping 3q28 amplifications in the COMA cell line and undifferentiated primary sarcoma

Hussenet T., Mallem N., Redon R., Jost B., Aurias A., du Manoir S.

Cancer Genet Cytogenet 2006; 169(2):102-13

Pitfalls of homozygosity mapping: an extended consanguineous Bardet-Biedl syndrome family with two mutant genes (BBS2, BBS10), three mutations, but no triallelism

Laurier V., Stoetzel C., Muller J., Thibault C., Corbani S., Jalkh N., Salem N., Chouery E., Poch O., Licaire S., Danse J.M., Amati-Bonneau P., Bonneau D., Megarbane A., Mandel J.L., Dollfus H.

Eur J Hum Genet 2006; 14(11):1195-203

Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program

Abou-Sleymane G., Chalmel F., Helmlinger D., Lardenois A., Thibault C., Weber C., Merienne K., Mandel J.L., Poch O., Devys D., Trottier Y.

Hum Mol Genet 2006; 15(5):691-703

Self-assembled small-molecule microarrays for protease screening and profiling

Urbina H.D., Debaene F., Jost B., Bole-Feysot C., Mason D.E., Kuzmic P., Harris J.L., Winssinger N.

Chembiochem 2006; 7(11):1790-7

Regulation of Rho signaling pathways in interleukin-2-stimulated human T-lymphocytes

Mzali R., Seguin L., Liot C., Auger A., Pacaud P., Loirand G., Thibault C., Pierre J., Bertoglio J.

Faseb J 2005; 19(13):1911-3

TAF4 inactivation in embryonic fibroblasts activates TGFbeta signalling and autocrine growth

Mengus G., Fadloun A., Kobi D., Thibault C., Perletti L., Michel I., Davidson I.

Embo J 2005; 24(15):2753-67

TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9

Frontini M., Soutoglou E., Argentini M., Bole-Feysot C., Jost B., Scheer E., Tora L.

Mol Cell Biol 2005; 25(11):4638-49

Using in vitro models for expression profiling studies on ethanol and drugs of abuse.

Thibault C, Hassan S, Miles M.

Addict Biol 2005; 10(1):53-62

Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis

Cromer A., Carles A., Millon R., Ganguli G., Chalmel F., Lemaire F., Young J., Dembele D., Thibault C., Muller D., Poch O., Abecassis J., Wasylyk B.

Oncogene 2004; 23(14):2484-98

Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood

Haddad R., Guardiola P., Izac B., Thibault C., Radich J., Delezoide A.L., Baillou C., Lemoine F.M., Gluckman J.C., Pflumio F., Canque B.

Blood 2004; 104(13):3918-26

Spatial and temporal expression of the zebrafish genome by large-scale in situ hybridization screening

Thisse B., Heyer V., Lux A., Alunni V., Degrave A., Seiliez I., Kirchner J., Parkhill J.P., Thisse C.

Methods Cell Biol 2004; 77():505-19

Fuzzy C-means method for clustering microarray data

Dembele D., Kastner P.

Bioinformatics 2003; 19(8):973-80

The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2

Pedron T., Thibault C., Sansonetti P.J.

J Biol Chem 2003; 278(36):33878-86

Amplicon mapping and transcriptional analysis pinpoint cyclin L as a candidate oncogene in head and neck cancer

Redon R., Hussenet T., Bour G., Caulee K., Jost B., Muller D., Abecassis J., du Manoir S.

Cancer Res 2002; 62(21):6211-7

Density of points clustering, application to transcriptomic data analysis

Wicker N., Dembele D., Raffelsberger W., Poch O.

Nucleic Acids Res 2002; 30(18):3992-4000

Quality indicators increase the reliability of microarray data

Raffelsberger W., Dembele D., Neubauer M.G., Gottardis M.M., Gronemeyer H.

Genomics 2002; 80(4):385-94

Complete sequence of the human RNA polymerase II largest subunit

Wintzerith M., Acker J., Vicaire S., Vigneron M., Kedinger C.

Nucleic Acids Res. 1992; 20():910


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